Single-minded may refer to:
Psychology
- Attention or focus
- Attentional control
- Determination
- Open-mindedness, receptivity to new ideas, contrasted with closed-mindedness
Religion
- Double-mindedness, a concept developed by Søren Kierkegaard from Christian tradition
- Ekaggata, a Buddhist term meaning tranquillity of mind or onepointedness
- James 1, a passage in the Christian Bible discussing double-mindedness
Science
- Single-minded (sim), a protein-coding gene in Drosophila, or its mammalian homologs SIM1 and SIM2
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