Spironema may refer to:
Animals:
- Spironema (gastropod), Spironema Meek, 1864 – a genus of Cretaceous sea snails
Plants:
- Spironema Raf. – sometimes considered a synonym of Cassytha L. (Lauraceae)
- Spironema Lindl. nom. illeg. hom. – a synonym of Callisia Loefl. (Commelinaceae)
- Spironema Hochst. nom. illeg. hom. – a synonym of Clerodendrum L. (Lamiaceae)
Protists:
- Spironema (flagellate), Spironema Klebs, 1893 nom. illeg. hom. – a synonym of Spironematella P. C. Silva, a genus of flagellate protists in the family Spironemidae.
Spirochaetes:
- Spironema Vuillemin, 1905 – a synonym of Treponema Schaudinn, 1905
Microsporidia:
- Spironema Léger & Hesse, 1924 – a synonym of Toxoglugea Léger & Hesse, 1924
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