Misplaced Pages

SrbA sRNA

Article snapshot taken from Wikipedia with creative commons attribution-sharealike license. Give it a read and then ask your questions in the chat. We can research this topic together.
Small regulatory non-coding RNA

SrbA (sRNA regulator of biofilms A) is a small regulatory non-coding RNA identified in pathogenic Pseudomonas aeruginosa. It is important for biofilm formation and pathogenicity. Bacterial strain with deleted SrbA had reduced biofilm mass. As the ability to form biofilms can contribute to the ability a pathogen to thrive within the host, the C. elegans hosts infected with the srbA deleted strain displayed significantly lower mortality rate than the wild-type strain. However, the deletion of srbA had no effect on growth or antibiotic resistance in P. aeruginosa.

See also

References

  1. Kerr KG, Snelling AM (December 2009). "Pseudomonas aeruginosa: a formidable and ever-present adversary". The Journal of Hospital Infection. 73 (4): 338–344. doi:10.1016/j.jhin.2009.04.020. PMID 19699552.
  2. Stewart PS, Franklin MJ (March 2008). "Physiological heterogeneity in biofilms". Nature Reviews. Microbiology. 6 (3): 199–210. doi:10.1038/nrmicro1838. PMID 18264116. S2CID 5477887.
  3. Taylor PK, Van Kessel AT, Colavita A, Hancock RE, Mah TF (2017). "A novel small RNA is important for biofilm formation and pathogenicity in Pseudomonas aeruginosa". PLOS ONE. 12 (8): e0182582. doi:10.1371/journal.pone.0182582. PMC 5542712. PMID 28771593.
Stub icon

This molecular or cell biology article is a stub. You can help Misplaced Pages by expanding it.

Categories: