Sulfite reductase (NADPH)

Sulfite reductase (NADPH) (EC 1.8.1.2, sulfite (reduced nicotinamide adenine dinucleotide phosphate) reductase, NADPH-sulfite reductase, NADPH-dependent sulfite reductase, H₂S-NADP oxidoreductase, sulfite reductase (NADPH₂)) is an enzyme with systematic name hydrogen-sulfide:NADP oxidoreductase. This enzyme catalises the following chemical reaction

hydrogen sulfide + 3 NADP + 3 H₂O

\rightleftharpoons

sulfite + 3 NADPH + 3 H

Sulfite reductase is an iron flavoprotein (FAD and FMN).

References

Hilz H, Kittler M, Knape G (1959). "". Biochemische Zeitschrift. 332: 151–66. PMID 14401842.
Siegel LM, Murphy MJ, Kamin H (January 1973). "Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. I. The Escherichia coli hemoflavoprotein: molecular parameters and prosthetic groups". The Journal of Biological Chemistry. 248 (1): 251–64. doi:10.1016/S0021-9258(19)44469-4. PMID 4144254.
Yoshimoto A, Sato R (April 1968). "Studies on yeast sulfite reductase. I. Purification and characterization". Biochimica et Biophysica Acta. 153 (3): 555–75. doi:10.1016/0005-2728(68)90185-0. PMID 4384979.

External links

Sulfite+reductase+(NADPH) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

v t e Oxidoreductases: sulfur oxidoreductases (EC 1.8)
1.8.1: NAD or NADP	Dihydrolipoamide dehydrogenase Glutathione reductase Thioredoxin reductase
1.8.2: cytochrome	Sulfite dehydrogenase Thiosulfate dehydrogenase Flavocytochrome c sulfide dehydrogenase
1.8.3: oxygen	Sulfite oxidase
1.8.4: disulfide	Glutathione—homocystine transhydrogenase
1.8.5: quinone	Glutathione dehydrogenase (ascorbate)
1.8.98: Other, known	CoB—CoM heterodisulfide reductase
1.8.99: Other	Sulfite reductase

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)

Portal:

Biology

Category:

EC 1.8.1