Misplaced Pages

Swain equation

Article snapshot taken from Wikipedia with creative commons attribution-sharealike license. Give it a read and then ask your questions in the chat. We can research this topic together.
Equation in chemical kinetics

The Swain equation relates the kinetic isotope effect for the protium/tritium combination with that of the protium/deuterium combination according to:

k H k T = ( k H k D ) 1.442 {\displaystyle {\frac {k_{H}}{k_{T}}}=({\frac {k_{H}}{k_{D}}})^{1.442}}

where kH,D,T are the reaction rate constants for the protonated, deuterated and tritiated reactants respectively.

External links

  1. Applied Swain equation

References

  1. Use of Hydrogen Isotope Effects to Identify the Attacking Nucleophile in the Enolization of Ketones Catalyzed by Acetic Acid C. Gardner Swain, Edward C. Stivers, Joseph F. Reuwer, Jr. Lawrence J. Schaad; J. Am. Chem. Soc.; 1958; 80(21); 5885-5893. doi:10.1021/ja01554a077
Categories: