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TMX3
Identifiers
Aliases	TMX3, PDIA13, TXNDC10, thioredoxin related transmembrane protein 3
External IDs	OMIM: 616102; MGI: 2442418; HomoloGene: 10381; GeneCards: TMX3; OMA:TMX3 - orthologs
Gene location (Mouse) Chr. Chromosome 18 (mouse) Band 18|18 E4 Start 90,528,278 bp End 90,561,391 bp
RNA expression pattern Bgee Human Mouse (ortholog) n/a Top expressed in otolith organ utricle hand superior cervical ganglion olfactory epithelium endothelial cell of lymphatic vessel supraoptic nucleus Epithelium of choroid plexus substantia nigra dorsomedial hypothalamic nucleus BioGPS More reference expression data
Gene ontology Molecular function protein binding isomerase activity thiol oxidase activity protein disulfide isomerase activity Cellular component integral component of membrane cell surface endoplasmic reticulum membrane endoplasmic reticulum membrane platelet alpha granule membrane plasma membrane Biological process peptidyl-cysteine oxidation protein folding response to endoplasmic reticulum stress cell redox homeostasis platelet degranulation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 54495 67988 Ensembl ENSG00000166479 ENSMUSG00000024614 UniProt Q96JJ7 Q8BXZ1 RefSeq (mRNA) NM_019022 NM_198295 RefSeq (protein) NP_061895 NP_001337441 NP_001337442 NP_001337443 NP_001337444 NP_001337445 NP_001337446 NP_938037 Location (UCSC) n/a Chr 18: 90.53 – 90.56 Mb PubMed search
Wikidata
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Protein disulfide-isomerase TMX3 is an enzyme that in humans is encoded by the TMX3 gene.

References

1. ^ GRCm38: Ensembl release 89: ENSMUSG00000024614 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. Haugstetter J, Blicher T, Ellgaard L (March 2005). "Identification and characterization of a novel thioredoxin-related transmembrane protein of the endoplasmic reticulum". The Journal of Biological Chemistry. 280 (9): 8371–8380. doi:10.1074/jbc.M413924200. PMID 15623505.
5. "Entrez Gene: TXNDC10 thioredoxin domain containing 10".

Further reading

• Hartley JL, Temple GF, Brasch MA (November 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–1795. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, et al. (March 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–435. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Nagase T, Nakayama M, Nakajima D, Kikuno R, Ohara O (April 2001). "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 8 (2): 85–95. doi:10.1093/dnares/8.2.85. PMID 11347906.
• Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, et al. (October 2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–2144. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, et al. (January 2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415 – D418. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Haugstetter J, Maurer MA, Blicher T, Pagac M, Wider G, Ellgaard L (November 2007). "Structure-function analysis of the endoplasmic reticulum oxidoreductase TMX3 reveals interdomain stabilization of the N-terminal redox-active domain". The Journal of Biological Chemistry. 282 (46): 33859–33867. doi:10.1074/jbc.M706442200. PMID 17881353.

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