Taxoid 7beta-hydroxylase | |||||||||
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Identifiers | |||||||||
EC no. | 1.14.13.147 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Taxoid 7beta-hydroxylase (EC 1.14.13.147) is an enzyme with systematic name taxusin,NADPH:oxygen 7-oxidoreductase. This enzyme catalyses the following chemical reaction
- taxusin + O2 + NADPH + H 7beta-hydroxytaxusin + NADP + H2O
Taxoid 7beta-hydroxylase requires cytochrome P450.
References
- Chau M, Jennewein S, Walker K, Croteau R (May 2004). "Taxol biosynthesis: Molecular cloning and characterization of a cytochrome P450 taxoid 7 beta-hydroxylase". Chemistry & Biology. 11 (5): 663–72. doi:10.1016/j.chembiol.2004.02.025. PMID 15157877.
External links
- Taxoid+7beta-hydroxylase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
Oxidoreductases: dioxygenases, including steroid hydroxylases (EC 1.14) | |
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1.14.11: 2-oxoglutarate | |
1.14.13: NADH or NADPH | |
1.14.14: reduced flavin or flavoprotein | |
1.14.15: reduced iron–sulfur protein | |
1.14.16: reduced pteridine (BH4 dependent) | |
1.14.17: reduced ascorbate | |
1.14.18-19: other | |
1.14.99 - miscellaneous |
Enzymes | |
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