Transphosphorylation is a chemical reaction in which a phosphate group or a phosphono group is transferred between a substrate and a receptor . There are various phosphate esters in living body including nucleic acid , and phosphorylation reaction related to their synthesis and interconversion is the basis of biochemical reaction. In most cases, ATP is the substrate of the phosphate group as a substrate and the enzyme that catalyzes these reactions is referred to as kinase .
References
Ardecky, Robert J.; Bobkova, Ekaterina V.; Kiffer-Moreira, Tina; Brown, Brock; Ganji, Santhi; Zou, Jiwen; Pass, Ian; Narisawa, Sonoko; Iano, Flávia Godoy; Rosenstein, Craig; Cheltsov, Anton; Rascon, Justin; Hedrick, Michael; Gasior, Carlton; Forster, Anita (2014-02-01). "Identification of a selective inhibitor of murine intestinal alkaline phosphatase (ML260) by concurrent ultra-high throughput screening against human and mouse isozymes" . Bioorganic & Medicinal Chemistry Letters . 24 (3): 1000–1004. doi :10.1016/j.bmcl.2013.12.043 . ISSN 1464-3405 . PMC 3943210 . PMID 24412070 .
Wang, Qian; Kang, Yoon-Suk; Alowaifeer, Abdullah; Shi, Kaixiang; Fan, Xia; Wang, Lu; Jetter, Jonathan; Bothner, Brian; Wang, Gejiao; McDermott, Timothy R. (2018-05-25). "Phosphate starvation response controls genes required to synthesize the phosphate analog arsenate" . Environmental Microbiology . 20 (5): 1782–1793. doi :10.1111/1462-2920.14108 . ISSN 1462-2920 . PMID 29575522 . S2CID 4700039 .
Tasnádi, Gábor; Zechner, Michaela; Hall, Mélanie; Baldenius, Kai; Ditrich, Klaus; Faber, Kurt (2017-10-06). "Investigation of acid phosphatase variants for the synthesis of phosphate monoesters" . Biotechnology and Bioengineering . 114 (10): 2187–2195. doi :10.1002/bit.26352 . ISSN 1097-0290 . PMID 28600898 . S2CID 25563592 .
Wan, Paul T. C.; Garnett, Mathew J.; Roe, S. Mark; Lee, Sharlene; Niculescu-Duvaz, Dan; Good, Valerie M.; Jones, C. Michael; Marshall, Christopher J.; Springer, Caroline J.; Barford, David; Marais, Richard; Cancer Genome Project (2004-03-19). "Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF" . Cell . 116 (6): 855–867. doi :10.1016/s0092-8674(04)00215-6 . ISSN 0092-8674 . PMID 15035987 .
Category :
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
**DISCLAIMER** We are not affiliated with Wikipedia, and Cloudflare.
The information presented on this site is for general informational purposes only and does not constitute medical advice.
You should always have a personal consultation with a healthcare professional before making changes to your diet, medication, or exercise routine.
AI helps with the correspondence in our chat.
We participate in an affiliate program. If you buy something through a link, we may earn a commission 💕
↑