Up in Smoke is a 1978 film featuring Cheech and Chong.
Up in Smoke may also refer to:
- Up in Smoke (album), the soundtrack to the 1978 film, or the title track also covered by Hank Williams III
- Up in Smoke (album), a 1995 album by Indo G and Lil' Blunt
- Up in Smoke (1957 film), starring the comedy team of The Bowery Boys
- Up in Smoke (2015 film), starring Naathan Phan
- "Up in Smoke" (CSI: Crime Scene Investigation), a sixth-season episode of CSI: Crime Scene Investigation
- "Up in Smoke" (NCIS), a ninth-season episode of NCIS
- Up in Smoke Tour, a West Coast hip hop tour which took place in 2000
- Up in Smoke, an alternate name used by the professional wrestling tag team Cheech and Cloudy
- "Up in Smoke", a song by Hollywood Undead from Notes from the Underground
- "Up in Smoke", a song by Lower Than Atlantis from World Record
- "Up in Smoke", a song by Neck Deep from A History of Bad Decisions
This disambiguation page lists articles associated with the title Up in Smoke.If an internal link led you here, you may wish to change the link to point directly to the intended article. Category: