VDI may refer to:
- Verein Deutscher Ingenieure, the Association of German Engineers
- Vidalia Regional Airport (IATA code: VDI)
- Vietnam Defence Industry, Vietnam's General Department of Defense Industry.
Technology
- Virtual Desktop Infrastructure, a Citrix/Microsoft desktop virtualization engine
- VDI (file format), the virtual disk image file used in VirtualBox systems
- Virtual Device Interface, a component of Digital Research's Graphics Environment Manager (GEM)
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