William Duke may refer to:
- William Duke (civil servant) (1863–1924), governor of Bengal
- William Duke (artist) (1814–1853), Irish-born Australian artist
- William Duke (mathematician) (born 1958), American mathematician
- William B. Duke (1857–1926), American Hall of Fame racehorse trainer
- William Mark Duke (1879–1971), Canadian archbishop
Topics referred to by the same termThis disambiguation page lists articles about people with the same name. If an internal link led you here, you may wish to change the link to point directly to the intended article. Category: