| Cyanobacterial functional RNA 1 | |
|---|---|
 Predicted secondary structure and sequence conservation of Yfr1 | |
| Identifiers | |
| Symbol | Yfr1 |
| Rfam | RF01116 |
| Other data | |
| RNA type | Gene; sRNA |
| Domain(s) | Bacteria |
| SO | SO:0001263 |
| PDB structures | PDBe |
Yfr1 is a Cyanobacterial functional RNA that was identified by a comparative genome based screen for RNAs in cyanobacteria. Further analysis has shown that the RNA is well conserved and highly expressed in cyanobacteria. and is required for growth under several stress condition Bioinformatics research combined with follow-up experiments have shown that Yfr1 inhibits the translation of the proteins PMM1119 and PMM1121 by an antisense interaction by base pairing at the ribosomal binding site.
See also
References
- Axmann IM, Kensche P, Vogel J, Kohl S, Herzel H, Hess WR (2005). "Identification of cyanobacterial non-coding RNAs by comparative genome analysis". Genome Biol. 6 (9): R73. doi:10.1186/gb-2005-6-9-r73. PMC 1242208. PMID 16168080.
- Voss B, Gierga G, Axmann IM, Hess WR (2007). "A motif-based search in bacterial genomes identifies the ortholog of the small RNA Yfr1 in all lineages of cyanobacteria". BMC Genomics. 8: 375. doi:10.1186/1471-2164-8-375. PMC 2190773. PMID 17941988.
- Nakamura T, Naito K, Yokota N, Sugita C, Sugita M (2007). "A cyanobacterial non-coding RNA, Yfr1, is required for growth under multiple stress conditions". Plant Cell Physiol. 48 (9): 1309–1318. doi:10.1093/pcp/pcm098. PMID 17664182.
- Richter AS, Schleberger C, Backofen R, Steglich C (2010). "Seed-based INTARNA prediction combined with GFP-reporter system identifies mRNA targets of the small RNA Yfr1". Bioinformatics. 26 (1): 1–5. doi:10.1093/bioinformatics/btp609. PMC 2796815. PMID 19850757.
External links
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