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Yunnanxane

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Yunnanxane
Names
Systematic IUPAC name 2,5,10-Triacetoxytaxa-4(20),11-dien-14-yl 3-hydroxy-2-methylbutanoate
Identifiers
CAS Number
3D model (JSmol)
ChEMBL
ChemSpider
PubChem CID
UNII
CompTox Dashboard (EPA)
SMILES
  • CC1(C)C((OC(C)=O)C2(C)(C((OC(C)=O)CC2)=C)()3OC(C)=O)=C(C)(OC((C)(C)O)=O)C13
Properties
Chemical formula C31H46O9
Molar mass 562.700 g·mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references
Chemical compound

Yunnanxane is a bioactive taxane diterpenoid first isolated from Taxus wallichiana. Yunnanxane was later isolated from cell cultures of Taxus cuspidata and Taxus chinensis. Four homologous esters of yunnanxane have also been isolated from Taxus. Yunnanxane is reported to have anticancer activity in vitro.

See also

References

  1. Chen WM, Zhang PL, Wu B, Zheng QT (1991). "[Studies on the chemical constituents of Taxus yunnanensis]". Yao Xue Xue Bao. 26 (10): 747–54. PMID 1688071.
  2. Ma W, Stahlhut RW, Adams TL, Park GL, Evans WA, Blumenthal SG, et al. (1994). "Yunnanxane and its homologous esters from cell cultures of Taxus chinensis var. mairei". J Nat Prod. 57 (9): 1320–4. doi:10.1021/np50111a027. PMID 7798969.


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