Zaikin (Russian: Заикин, IPA: [zɐˈikʲɪn]) is a Russian surname meaning literally "stutterer's (son)". Notable people with the surname include:
- Aleksandr Vladimirovich Zaikin (born 1988), Russian footballer
- Aleksandr Yevgenyevich Zaikin (born 1974), Russian footballer
- Dmitri Zaikin (1932-2013), Russian cosmonaut trainer
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