Zaydan is a surname. Notable people with the surname include:
- Banu Zaydan, Arab clan that dominated the Galilee late 17th-early 18th centuries
- Amina Zaydan (born 1966), Egyptian novelist
- Hasan Zaydan, Iraqi politician
- Ibn Zaydan (1878–1946), Moroccan historian and literary author
- Jurji Zaydan (1861–1914), Lebanese novelist
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