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{{DISPLAYTITLE:''n''-Propyl azide}} | {{DISPLAYTITLE:''n''-Propyl azide}} | ||
{{chembox | {{chembox | ||
| Verifiedfields = changed | |||
| Watchedfields = changed | | Watchedfields = changed | ||
| verifiedrevid = |
| verifiedrevid = 420919817 | ||
| Name = ''n''-Propyl azide | | Name = ''n''-Propyl azide | ||
| ImageFile = Propyl azide.svg | | ImageFile = Propyl azide.svg | ||
| ImageAlt = Skeletal formula of propyl azide | |||
| ImageSize = | |||
| ImageFile1 = Propyl-azide-3D-balls.png | |||
⚫ | | |
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| ImageSize1 = 190 | |||
| ImageAlt1 = Ball-and-stick model of the propyl azide molecule | |||
⚫ | | PIN = 1-Azidopropane | ||
| OtherNames = | | OtherNames = | ||
| |
|Section1={{Chembox Identifiers | ||
| CASNo =22293-25-0 | | CASNo =22293-25-0 | ||
| |
| CASNo_Ref = {{cascite|correct|CAS}} | ||
| PubChem = | | PubChem = 12405072 | ||
| SMILES ===NCCC | | SMILES ===NCCC | ||
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | |||
| ChemSpiderID = 14073926 | |||
| InChI = 1/C3H7N3/c1-2-3-5-6-4/h2-3H2,1H3 | |||
| InChIKey = TVPPZASKIXGUJQ-UHFFFAOYAK | |||
| StdInChI_Ref = {{stdinchicite|changed|chemspider}} | |||
| StdInChI = 1S/C3H7N3/c1-2-3-5-6-4/h2-3H2,1H3 | |||
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | |||
| StdInChIKey = TVPPZASKIXGUJQ-UHFFFAOYSA-N | |||
}} | }} | ||
| |
|Section2={{Chembox Properties | ||
| C=3 | H=7 | N=3 | | C=3 | H=7 | N=3 | ||
| Appearance = | | Appearance = | ||
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| SolubleOther = | | SolubleOther = | ||
}} | }} | ||
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|Section3={{Chembox Explosive | ||
| ShockSens = | | ShockSens = | ||
| FrictionSens = | | FrictionSens = | ||
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| DetonationV = | ||
| REFactor = }} | | REFactor = }} | ||
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|Section4={{Chembox Hazards | ||
| MainHazards = Harmful, Explosive | | MainHazards = Harmful, Explosive | ||
| FlashPt = | | FlashPt = | ||
| |
| AutoignitionPt = }} | ||
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|Section8={{Chembox Related | ||
| OtherAnions = | | OtherAnions = | ||
| OtherCations = | | OtherCations = | ||
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| OtherFunction = | ||
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| OtherFunction_label = | ||
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| OtherCompounds = ], ], ] }} | ||
}} | }} | ||
'''''n''-Propyl azide''' is an ] with the formula CH<sub>3</sub>CH<sub>2</sub>CH<sub>2</sub>N<sub>3</sub>. A white solid, it is a simple ]. | |||
<ref>Stefan Bräse (Editor), Klaus Banert (Co-Editor); ''Organic Azides: Syntheses and Applications''; 2010 ]; {{ISBN|978-0-470-51998-1}}</ref> | |||
''n''-Propyl azide has been used in the laboratory synthesis of pharmaceutical drug candidates.<ref>{{Cite journal | author = Helmut Haning |
''n''-Propyl azide has been used in the laboratory synthesis of pharmaceutical drug candidates.<ref>{{Cite journal | author = Helmut Haning| title = Comparison of different heterocyclic scaffolds as substrate analog PDE5 inhibitors | journal = ] | year = 2005 | volume = 15 | issue = 17 | pages = 3900–3907 | doi=10.1016/j.bmcl.2005.05.090| pmid = 15993055 |display-authors=etal}}</ref><ref>{{cite journal | author = Michael H. Parker| title = Synthesis of (−)-5,8-Dihydroxy-3R-methyl-2R-(dipropylamino)-1,2,3,4-tetrahydronaphthalene: An Inhibitor of β-Amyloid<sub>1-42</sub> Aggregation | journal = ] | year = 2002 | volume = 10 | issue = 11 | pages = 3565–3569 | doi=10.1016/s0968-0896(02)00251-1|display-authors=etal | pmid=12213471}}</ref> | ||
==References== | ==References== | ||
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==Further reading== | ==Further reading== | ||
* {{cite journal | author = Edward J. Kaufmann, Richard C. Thompson | title = Reduction of organic azides by chromium(II) in aqueous solution | journal = ] | year = 1977 | volume = 99 | issue = 6 | pages = 1824–1830 | doi = 10.1021/ja00448a025}} | * {{cite journal | author = Edward J. Kaufmann, Richard C. Thompson | title = Reduction of organic azides by chromium(II) in aqueous solution | journal = ] | year = 1977 | volume = 99 | issue = 6 | pages = 1824–1830 | doi = 10.1021/ja00448a025}} | ||
{{DEFAULTSORT:Propyl azide, n-}} | {{DEFAULTSORT:Propyl azide, n-}} | ||
] | ] | ||
] | |||
Latest revision as of 07:36, 19 July 2023
Names | |
---|---|
Preferred IUPAC name 1-Azidopropane | |
Identifiers | |
CAS Number | |
3D model (JSmol) | |
ChemSpider | |
PubChem CID | |
CompTox Dashboard (EPA) | |
InChI
| |
SMILES
| |
Properties | |
Chemical formula | C3H7N3 |
Molar mass | 85.110 g·mol |
Hazards | |
Occupational safety and health (OHS/OSH): | |
Main hazards | Harmful, Explosive |
Related compounds | |
Related compounds | Hydrazoic acid, Chlorine azide, Ethyl azide |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). N verify (what is ?) Infobox references |
n-Propyl azide is an organic compound with the formula CH3CH2CH2N3. A white solid, it is a simple organic azide.
n-Propyl azide has been used in the laboratory synthesis of pharmaceutical drug candidates.
References
- Stefan Bräse (Editor), Klaus Banert (Co-Editor); Organic Azides: Syntheses and Applications; 2010 John Wiley and Sons; ISBN 978-0-470-51998-1
- Helmut Haning; et al. (2005). "Comparison of different heterocyclic scaffolds as substrate analog PDE5 inhibitors". Bioorganic & Medicinal Chemistry Letters. 15 (17): 3900–3907. doi:10.1016/j.bmcl.2005.05.090. PMID 15993055.
- Michael H. Parker; et al. (2002). "Synthesis of (−)-5,8-Dihydroxy-3R-methyl-2R-(dipropylamino)-1,2,3,4-tetrahydronaphthalene: An Inhibitor of β-Amyloid1-42 Aggregation". Bioorganic & Medicinal Chemistry. 10 (11): 3565–3569. doi:10.1016/s0968-0896(02)00251-1. PMID 12213471.
Further reading
- Edward J. Kaufmann, Richard C. Thompson (1977). "Reduction of organic azides by chromium(II) in aqueous solution". Journal of the American Chemical Society. 99 (6): 1824–1830. doi:10.1021/ja00448a025.
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