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{{Short description|Chemical compound}}
{{drugbox
{{Drugbox
| Verifiedfields = changed
| verifiedrevid = 486407352
⚫ | IUPAC_name = 4,5,6,7-tetrabromo-2-hydroxy-1,3,2-benzodioxabismole
⚫ | image = Bibrocathol structure a.svg

<!--Clinical data-->
| tradename = Noviform, Posiformin
| Drugs.com = {{drugs.com|international|bibrocathol}}
⚫ | pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
⚫ | pregnancy_US = <!-- A / B / C / D / X -->
⚫ | pregnancy_category =
⚫ | legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
⚫ | legal_CA = <!-- Schedule I, II, III, IV, V, VI, VII, VIII -->
⚫ | legal_UK = <!-- GSL, P, POM, CD, or Class A, B, C -->
⚫ | legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
⚫ | legal_status =
⚫ | routes_of_administration = Topical (eye ointment)

<!--Pharmacokinetic data-->
⚫ | bioavailability =
⚫ | protein_bound =
⚫ | metabolism =
⚫ | elimination_half-life =
⚫ | excretion =

<!--Identifiers-->
| CAS_number_Ref = {{cascite|changed|??}}
⚫ | CAS_number = 6915-57-7
⚫ | ATC_prefix = S01
⚫ | ATC_suffix = AX05
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
⚫ | StdInChI = 1S/C6H2Br4O2.Bi.H2O/c7-1-2(8)4(10)6(12)5(11)3(1)9;;/h11-12H;;1H2/q;+3;/p-3
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
⚫ | StdInChIKey = VTAVFIZOZUAKKE-UHFFFAOYSA-K
⚫ | PubChem = 16683103
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
⚫ | DrugBank =
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
⚫ | ChemSpiderID = 11232581
| UNII_Ref = {{fdacite|correct|FDA}} | UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 0KJ20H1BLJ | UNII = 0KJ20H1BLJ
| ChEMBL_Ref = {{ebicite|correct|EBI}}
⚫ | IUPAC_name = 4,5,6,7-tetrabromo-2-hydroxy-1,3,2-benzodioxabismole
⚫ | image = Bibrocathol structure.svg
⚫ | InChI = 1/C6H2Br4O2.Bi.H2O/c7-1-2(8)4(10)6(12)5(11)3(1)9;;/h11-12H;;1H2/q;+3;/p-3/rC6HBiBr4O3/c8-1-2(9)4(11)6-5(3(1)10)13-7(12)14-6/h12H
⚫ | InChIKey = VTAVFIZOZUAKKE-AJXSUKGNAS
⚫ | CAS_number = 6915-57-7
⚫ | ATC_prefix = S01
⚫ | ATC_suffix = AX05
⚫ | PubChem = 16683103
⚫ | DrugBank =
⚫ | ChemSpiderID = 11232581
| ChEMBL = 44875 | ChEMBL = 44875

⚫ | chemical_formula =
<!--Chemical data-->
⚫ | chemical_formula =
| C=6 | H=1 | Bi=1 | Br=4 | O=3 | C=6 | H=1 | Bi=1 | Br=4 | O=3
⚫ | smiles = O1Oc2c(Br)c(Br)c(Br)c(Br)c2O1
| molecular_weight = 650.675 g/mol
⚫ | synonyms = Bibrocathin<br>Tetrabromopyrocatechol&nbsp;bismuth
⚫ | smiles = O1Oc2c(Br)c(Br)c(Br)c(Br)c2O1
⚫ | synonyms = Bibrocathin<br>Tetrabromopyrocatechol&nbsp;bismuth
⚫ | bioavailability =
⚫ | protein_bound =
⚫ | metabolism =
⚫ | elimination_half-life =
⚫ | excretion =
⚫ | pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
⚫ | pregnancy_US = <!-- A / B / C / D / X -->
⚫ | pregnancy_category=
⚫ | legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
⚫ | legal_CA = <!-- Schedule I, II, III, IV, V, VI, VII, VIII -->
⚫ | legal_UK = <!-- GSL, P, POM, CD, or Class A, B, C -->
⚫ | legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
⚫ | legal_status =
⚫ | routes_of_administration = Topical (eye ointment)
}} }}
'''Bibrocathol''' (], trade names '''Noviform''' and '''Posiformin''') is the substance 4,5,6,7-Tetrabrom-1,3,2-benzodioxabismol-2-ol. It contains ] and is used to treat eye infections and control swelling. '''Bibrocathol''' (]; trade names '''Noviform''' and '''Posiformin''') is a pharmaceutical ]. Its chemical name is 4,5,6,7-tetrabrom-1,3,2-benzodioxabismol-2-ol. It contains ] and is used to treat eye infections and control swelling.<ref>{{cite book | vauthors = Gurtler L | chapter = Chapter 2: The Eye and Conjunctiva as Target of Entry for Infectious Agents: Prevention by Protection and by Antiseptic Prophylaxis | veditors = Kramer A, Behrens-Baumann W |title=Antiseptic prophylaxis and therapy in ocular infections: principles, clinical practice, and infection control | series = Developments in Ophthalmology |date= January 2002 | volume = 33 | pages = 9–13 |publisher=Karger |location=Basel |isbn=978-3-8055-7316-0 | doi = 10.1159/000065934 | pmid = 12236131 | chapter-url = https://books.google.com/books?id=JkQOSAnOIhoC&dq=Bibrocathol&pg=PA96 }}</ref>


== References ==
⚫ ]
{{Reflist}}
⚫ ]

]
==External links==
* {{Commonscatinline}}


{{Bismuth compounds}} {{Bismuth compounds}}
⚫ {{antiinfective-drug-stub}}


] ]
]
]
⚫ ]
⚫ ]
]

⚫ {{antiinfective-drug-stub}}

Latest revision as of 16:34, 5 December 2024

Chemical compound Pharmaceutical compound
Bibrocathol
Clinical data
Trade namesNoviform, Posiformin
Other namesBibrocathin
Tetrabromopyrocatechol bismuth
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Topical (eye ointment)
ATC code
Identifiers
IUPAC name
  • 4,5,6,7-tetrabromo-2-hydroxy-1,3,2-benzodioxabismole
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.027.294 Edit this at Wikidata
Chemical and physical data
FormulaC6HBiBr4O3
Molar mass649.667 g·mol
3D model (JSmol)
SMILES
  • O1Oc2c(Br)c(Br)c(Br)c(Br)c2O1
InChI
  • InChI=1S/C6H2Br4O2.Bi.H2O/c7-1-2(8)4(10)6(12)5(11)3(1)9;;/h11-12H;;1H2/q;+3;/p-3
  • Key:VTAVFIZOZUAKKE-UHFFFAOYSA-K
  (what is this?)  (verify)

Bibrocathol (INN; trade names Noviform and Posiformin) is a pharmaceutical antiseptic. Its chemical name is 4,5,6,7-tetrabrom-1,3,2-benzodioxabismol-2-ol. It contains bismuth and is used to treat eye infections and control swelling.

References

  1. Gurtler L (January 2002). "Chapter 2: The Eye and Conjunctiva as Target of Entry for Infectious Agents: Prevention by Protection and by Antiseptic Prophylaxis". In Kramer A, Behrens-Baumann W (eds.). Antiseptic prophylaxis and therapy in ocular infections: principles, clinical practice, and infection control. Developments in Ophthalmology. Vol. 33. Basel: Karger. pp. 9–13. doi:10.1159/000065934. ISBN 978-3-8055-7316-0. PMID 12236131.

External links

Bismuth compounds
Bismuth(III)
Organobismuth(III)
Bismuth(V)
Organobismuth(V)
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