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Acetarsol

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Acetarsol
Structural formula of acetarsol
Names
Preferred IUPAC name Acetarsone
Systematic IUPAC name (3-Acetamido-4-hydroxyphenyl)arsonic acid
Other names 3-Acetamido-4-hydroxyphenylarsonic acid
Identifiers
CAS Number
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.002.349 Edit this at Wikidata
EC Number
  • 202-582-3
KEGG
MeSH Acetarsol
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C8H10AsNO5/c1-5(11)10-7-4-6(9(13,14)15)2-3-8(7)12/h2-4,12H,1H3,(H,10,11)(H2,13,14,15)Key: ODFJOVXVLFUVNQ-UHFFFAOYSA-N
  • InChI=1/C8H10AsNO5/c1-5(11)10-7-4-6(9(13,14)15)2-3-8(7)12/h2-4,12H,1H3,(H,10,11)(H2,13,14,15)Key: ODFJOVXVLFUVNQ-UHFFFAOYAX
SMILES
  • O=(O)(O)c1ccc(O)c(NC(=O)C)c1
  • CC(=O)NC1=CC(=CC=C1O)(O)(O)=O
Properties
Chemical formula C8H10AsNO5
Molar mass 275.092 g·mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references
Chemical compound

Acetarsol is an anti-infective.

It was first discovered in 1921 at Pasteur Institute by Ernest Fourneau ], and sold under the brand name Stovarsol (fourneau is the French word for stove).

It has been given in suppositories.

References

  1. Chen MY, Smith NA, Fox EF, Bingham JS, Barlow D (1999). "Acetarsol pessaries in the treatment of metronidazole resistant Trichomonas vaginalis". Int J STD AIDS. 10 (4): 277–80. doi:10.1258/0956462991913943. PMID 12035784. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  2. Éric Fouassier, Ces poisons qui guérissent, oct. 1996, p. 5.
  3. Traité de chimie organique, sous la direction de Victor Grignard, Paul Baud, vol. 22, Masson, 1959, p. 1127-1130.
  4. Gionchetti P, Rizzello F, Morselli C, Campieri M (2004). "Review article: problematic proctitis and distal colitis". Aliment. Pharmacol. Ther. 20 Suppl 4: 93–6. doi:10.1111/j.1365-2036.2004.02049.x. PMID 15352902. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
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