Broxyquinoline - Misplaced Pages

Chemical compound Pharmaceutical compound

Broxyquinoline
Clinical data


AHFS/Drugs.com	International Drug Names
ATC code	A07AX01 (WHO) G01AC06 (WHO) P01AA01 (WHO)
Identifiers
IUPAC name 5,7-Dibromoquinolin-8-ol
CAS Number	521-74-4
PubChem CID	2453
ChemSpider	2359
UNII	UK4C618C8T
ChEMBL	ChEMBL223448
CompTox Dashboard (EPA)	DTXSID9045849
ECHA InfoCard	100.007.563
Chemical and physical data
Formula	C₉H₅Br₂NO
Molar mass	302.953 g·mol
3D model (JSmol)	Interactive image
SMILES Brc1c(O)c2ncccc2c(Br)c1
InChI InChI=1S/C9H5Br2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H Key:ZDASUJMDVPTNTF-UHFFFAOYSA-N
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Broxyquinoline is an antiprotozoal agent.An association with exercise intolerance has been reported.

References

Swain R, Bapna JS (January 1986). "Impairment of exercise tolerance due to broxyquinoline-brobenzoxaldine combination". Human Toxicology. 5 (1): 63–4. doi:10.1177/096032718600500115. PMID 3081430. S2CID 23922563.

v t e Antidiarrheals, intestinal anti-inflammatory and anti-infective agents (A07)
Rehydration	Oral rehydration therapy
Intestinal anti-infectives	Antibiotics Amphotericin B Colistin Fidaxomicin Kanamycin Natamycin Neomycin Nystatin Paromomycin Polymyxin B Rifaximin Streptomycin Vancomycin Sulfonamides Phthalylsulfathiazole Succinylsulfathiazole Sulfaguanidine Nitrofuran Nifuroxazide Nifurzide Imidazole Miconazole Arsenical Acetarsol Oxyquinoline Broxyquinoline
Intestinal adsorbents	Charcoal Bismuth (including bismuth subsalicylate, known as Pepto-Bismol) Pectin Kaolin Crospovidone Attapulgite Diosmectite
Antipropulsives (opioids)	Opium tincture (laudanum) Codeine Morphine Camphorated opium tincture (paregoric) crosses BBB: Diphenoxylate (+atropine) Difenoxin does not cross BBB: Eluxadoline Loperamide (+simethicone)
Intestinal anti-inflammatory agents	corticosteroids acting locally Prednisolone Hydrocortisone Prednisone Betamethasone Tixocortol Budesonide Beclometasone antiallergic agents, excluding corticosteroids Cromoglicic acid Aminosalicylates Sulfasalazine Mesalazine Olsalazine Balsalazide
Antidiarrheal micro-organisms	Escherichia coli Saccharomyces boulardii
Other antidiarrheals	Albumin tannate Bismuth subsalicylate Ceratonia Crofelemer Octreotide Racecadotril Kaopectate
WHO-EM Withdrawn from market Clinical trials: Phase III Never to phase III

Nitroimidazole derivatives	Metronidazole Tinidazole Ornidazole Nimorazole Secnidazole Azanidazole Propenidazole
Other	isoquinoline (Emetine/Dehydroemetine)

Other/ungrouped

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