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Arofylline

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Arofylline
Names
IUPAC name 3-(4-Chlorophenyl)-1-propyl-7H-purine-2,6-dione
Identifiers
CAS Number
3D model (JSmol)
ChEMBL
ChemSpider
PubChem CID
CompTox Dashboard (EPA)
SMILES
  • CCCN1C(=O)C2=C(N=CN2)N(C1=O)C3=CC=C(C=C3)Cl
Properties
Chemical formula C14H13ClN4O2
Molar mass 304.73 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references
Chemical compound

Arofylline (codenamed LAS 31025) is a phosphodiesterase inhibitor.

References

  1. Ferrer, L; Alberola, J; Queralt, M; Brazís, P; Rabanal, R; Llenas, J; Puigdemont, A (1999). "Clinical anti-inflammatory efficacy of arofylline, a new selective phosphodiesterase-4 inhibitor, in dogs with atopic dermatitis". The Veterinary Record. 145 (7): 191–4. PMID 10501583.
Phosphodiesterase inhibitors
PDE1
PDE2
PDE3
PDE4
PDE5
PDE7
PDE9
PDE10
PDE11BC11-38
Non-selective
Unsorted
See also: Receptor/signaling modulators
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