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Irsogladine

Names
Preferred IUPAC name 6-(2,5-Dichlorophenyl)1,3,5-triazine-2,4-diamine
Other names DCPDAT, Dicloguamine, MN-1695.
Identifiers
CAS Number	57381-26-7
ChemSpider	3621
PubChem CID	3752
UNII	QBX79NZC1D
CompTox Dashboard (EPA)	DTXSID8043999
Properties
Chemical formula	C9H7Cl2N5
Molar mass	256.09 g·mol
Pharmacology
ATC code	A02BX16 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Infobox references

Irsogladine is a phosphodiesterase inhibitor.

Antiulcer drug.

Synthesis

2,4-Dichloro-6-(2,5-dichlorophenyl)-1,3,5-triazine (1) (2) Dicyandiamide (3) 2,5-Dichlorobenzonitrile (4)

References

1. Satoh, H; Amagase, K; Takeuchi, K (2013). "Mucosal protective agents prevent exacerbation of NSAID-induced small intestinal lesions caused by antisecretory drugs in rats". The Journal of Pharmacology and Experimental Therapeutics. 348 (2): 227–35. doi:10.1124/jpet.113.208991. PMID 24254524. S2CID 23740642.
2. Serradell, MN; Blancafort, P.; Castaer, J.; MN-1695. Drugs Fut 1983, 8, 6, 502.
3. Ueda F, Aratani S, Mimura K, Kimura K, Nomura A, Enomoto H. Effect of 2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate (MN-1695) on gastric ulcers and gastric secretion in experimental animals. Arzneimittelforschung. 1984;34(4):474-7. PMID: 654016.
4. DE2506814 idem Hiromu Murai, 6 More », U.S. patent 3,966,728 (1976 to Nippon Shinyaku Co., Ltd.).

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