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Aspartyl aminopeptidase

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Class of enzymes
Aspartyl aminopeptidase
Aspartyl aminopeptidase dodekamer, Bos taurus
Identifiers
EC no.3.4.11.21
CAS no.9074-83-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

Aspartyl aminopeptidase (EC 3.4.11.21) is an enzyme. This enzyme catalyses the following chemical reaction

Release of an N-terminal aspartate or glutamate from a peptide, with a preference for aspartate

Aminoacyl-arylamides are poor substrates.

References

  1. Kelly JA, Neidle EL, Neidle A (June 1983). "An aminopeptidase from mouse brain cytosol that cleaves N-terminal acidic amino acid residues". Journal of Neurochemistry. 40 (6): 1727–34. doi:10.1111/j.1471-4159.1983.tb08148.x. PMID 6854330. S2CID 25470156.
  2. Wilk S, Wilk E, Magnusson RP (June 1998). "Purification, characterization, and cloning of a cytosolic aspartyl aminopeptidase". The Journal of Biological Chemistry. 273 (26): 15961–70. doi:10.1074/jbc.273.26.15961. PMID 9632644.

External links

Hydrolase: proteases (EC 3.4)
3.4.11-19: Exopeptidase
3.4.11
3.4.13
3.4.14
3.4.15
3.4.16
3.4.17
Metalloexopeptidases
Carboxypeptidase
A
A2
B
C
E
Glutamate II
Other/ungrouped
3.4.21-25: Endopeptidase
3.4.99: Unknown
Enzymes
Activity
Regulation
Classification
Kinetics
Types
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