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CDP-glycerol glycerophosphotransferase

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CDP-glycerol glycerophosphotransferase
Identifiers
EC no.2.7.8.12
CAS no.9076-71-5
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In enzymology, a CDP-glycerol glycerophosphotransferase (EC 2.7.8.12) is an enzyme that catalyzes the chemical reaction

CDP-glycerol + (glycerophosphate)n {\displaystyle \rightleftharpoons } CMP + (glycerophosphate)n+1

Thus, the two substrates of this enzyme are CDP-glycerol and (glycerophosphate)n, whereas its two products are CMP and (glycerophosphate)n+1.

This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase. Other names in common use include teichoic-acid synthase, cytidine diphosphoglycerol glycerophosphotransferase, poly(glycerol phosphate) polymerase, teichoic acid glycerol transferase, glycerophosphate synthetase, and CGPTase.

References

  • BURGER MM, GLASER L (1964). "THE SYNTHESIS OF TEICHOIC ACIDS. I. POLYGLYCEROPHOSPHATE". J. Biol. Chem. 239: 3168–77. PMID 14245357.
Transferases: phosphorus-containing groups (EC 2.7)
2.7.1-2.7.4:
phosphotransferase/kinase
(PO4)
2.7.1: OH acceptor
2.7.2: COOH acceptor
2.7.3: N acceptor
2.7.4: PO4 acceptor
2.7.6: diphosphotransferase
(P2O7)
2.7.7: nucleotidyltransferase
(PO4-nucleoside)
Polymerase
DNA polymerase
DNA-directed DNA polymerase
I/A
γ
θ
ν
T7
Taq
II/B
α
δ
ε
ζ
Pfu
III/C
IV/X
β
λ
μ
TDT
V/Y
η
ι
κ
RNA-directed DNA polymerase
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RNA polymerase I
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III
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V
ssRNAP
POLRMT
Primase
1
2
PrimPol
RNA-dependent RNA polymerase
Polyadenylation
PAP
PNPase
Phosphorolytic
3' to 5' exoribonuclease
Nucleotidyltransferase
Guanylyltransferase
Other
2.7.8: miscellaneous
Phosphatidyltransferases
Glycosyl-1-phosphotransferase
2.7.10-2.7.13: protein kinase
(PO4; protein acceptor)
2.7.10: protein-tyrosine
2.7.11: protein-serine/threonine
2.7.12: protein-dual-specificity
2.7.13: protein-histidine
Enzymes
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