CDP-glycerol glycerophosphotransferase | |||||||||
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Identifiers | |||||||||
EC no. | 2.7.8.12 | ||||||||
CAS no. | 9076-71-5 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a CDP-glycerol glycerophosphotransferase (EC 2.7.8.12) is an enzyme that catalyzes the chemical reaction
- CDP-glycerol + (glycerophosphate)n CMP + (glycerophosphate)n+1
Thus, the two substrates of this enzyme are CDP-glycerol and (glycerophosphate)n, whereas its two products are CMP and (glycerophosphate)n+1.
This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase. Other names in common use include teichoic-acid synthase, cytidine diphosphoglycerol glycerophosphotransferase, poly(glycerol phosphate) polymerase, teichoic acid glycerol transferase, glycerophosphate synthetase, and CGPTase.
References
- BURGER MM, GLASER L (1964). "THE SYNTHESIS OF TEICHOIC ACIDS. I. POLYGLYCEROPHOSPHATE". J. Biol. Chem. 239: 3168–77. PMID 14245357.
Transferases: phosphorus-containing groups (EC 2.7) | |||||||||||||||
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2.7.1-2.7.4: phosphotransferase/kinase (PO4) |
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2.7.6: diphosphotransferase (P2O7) | |||||||||||||||
2.7.7: nucleotidyltransferase (PO4-nucleoside) |
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2.7.8: miscellaneous |
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2.7.10-2.7.13: protein kinase (PO4; protein acceptor) |
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