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Iron(II) fumarate

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Iron(II) fumarate
Names
IUPAC name Iron(2+) (2E)-but-2-enedioate
Other names Ferrous fumarate; Feostat
Identifiers
CAS Number
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.004.953 Edit this at Wikidata
PubChem CID
UNII
CompTox Dashboard (EPA)
InChI
  • InChI=1S/C4H4O4.Fe/c5-3(6)1-2-4(7)8;/h1-2H,(H,5,6)(H,7,8);/q;+2/p-2/b2-1+;Key: PMVSDNDAUGGCCE-TYYBGVCCSA-L
  • InChI=1/C4H4O4.Fe/c5-3(6)1-2-4(7)8;/h1-2H,(H,5,6)(H,7,8);/q;+2/p-2/b2-1+;Key: PMVSDNDAUGGCCE-FMKVMNOJBF
SMILES
  • .C(=O)/C=C/C()=O
Properties
Chemical formula C4H2FeO4
Molar mass 169.901 g·mol
Appearance reddish-brown powder
Odor odorless
Density 2.435 g/cm (20 °C)
Melting point 280 °C (536 °F; 553 K)
Solubility in water slightly soluble
Pharmacology
ATC code B03AA02 (WHO)
Hazards
NFPA 704 (fire diamond)
NFPA 704 four-colored diamondHealth 1: Exposure would cause irritation but only minor residual injury. E.g. turpentineFlammability 0: Will not burn. E.g. waterInstability 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g. liquid nitrogenSpecial hazards (white): no code
1 0 0
Lethal dose or concentration (LD, LC):
LD50 (median dose) 3850 mg/kg (oral, rat)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). ☒N verify (what is  ?) Infobox references
Chemical compound

Iron(II) fumarate, also known as ferrous fumarate, is the iron(II) salt of fumaric acid, occurring as a reddish-orange powder, used to supplement iron intake. It has the chemical formula C4H2FeO4. Pure ferrous fumarate has an iron content of 32.87%, therefore one tablet of 300 mg iron fumarate will contain 98.6 mg of iron (548% Daily Value based on 18 mg RDI).

Iron supplement

Ferrous fumarate is often taken orally as an iron supplement to treat or prevent iron deficiency anemia. Mixtures of ferrous fumarate and potassium iodate, "double fortified salt", are used to address both iron and iodine deficiencies.

See also

References

  1. Santiago, Palacios (2012-05-02). "Ferrous versus Ferric Oral Iron Formulations for the Treatment of Iron Deficiency: A Clinical Overview". The Scientific World Journal. 2012: e846824. doi:10.1100/2012/846824. ISSN 2356-6140. PMC 3354642. PMID 22654638.
  2. Diosady, Levente L.; Mannar, M.G. Venkatesh; Krishnaswamy, Kiruba (2019). "Improving the lives of millions through new double fortification of salt technology". Maternal & Child Nutrition. 15 (Suppl 3): e12773. doi:10.1111/mcn.12773. PMC 6594086. PMID 31148400.
Antianemic preparations (B03)
Erythropoietins
Iron supplements
Vitamin B12 and
folic acid supplements
HIF prolyl-hydroxylase inhibitors
Other
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