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Fluocortin butyl

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Chemical compound Pharmaceutical compound
Fluocortin butyl
Clinical data
Trade namesLenen, Novoderm, Varlane, Vaspit
Other namesFCB; SHK-203; Fluocortin 21-butylate; Fluocortin butylate; Fluocortolone-21-carboxylate 21-butyl; 6α-Fluoro-11β-hydroxy-16α-methyl-3,20-dioxopregna-1,4-dien-21-oic acid butyl ester
Drug classCorticosteroid; Glucocorticoid
Identifiers
IUPAC name
  • Butyl 2-phenanthren-17-yl]-2-oxoacetate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.050.476 Edit this at Wikidata
Chemical and physical data
FormulaC26H35FO5
Molar mass446.559 g·mol
3D model (JSmol)
SMILES
  • CCCCOC(=O)C(=O)1(C21(C(32C(C4=CC(=O)C=C34C)F)O)C)C
InChI
  • InChI=1S/C26H35FO5/c1-5-6-9-32-24(31)23(30)21-14(2)10-17-16-12-19(27)18-11-15(28)7-8-25(18,3)22(16)20(29)13-26(17,21)4/h7-8,11,14,16-17,19-22,29H,5-6,9-10,12-13H2,1-4H3/t14-,16+,17+,19+,20+,21-,22-,25+,26+/m1/s1
  • Key:XWTIDFOGTCVGQB-FHIVUSPVSA-N

Fluocortin butyl (brand names Lenen, Novoderm, Varlane, Vaspit), or fluocortin 21-butylate, is a synthetic glucocorticoid corticosteroid which is marketed in Germany, Belgium, Luxembourg, Spain, and Italy. Chemically, it is the butyl ester derivative of fluocortin.

It was patented in 1971 and approved for medical use in 1977.

References

  1. ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 563–. ISBN 978-1-4757-2085-3.
  2. ^ Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 457–. ISBN 978-3-88763-075-1.
  3. Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 487. ISBN 9783527607495.
Glucocorticoids and antiglucocorticoids (D07, H02)
Glucocorticoids
Natural
Synthetic
Antiglucocorticoids
Synthesis modifiers
See also
Glucocorticoid receptor modulators
Mineralocorticoids and antimineralocorticoids
List of corticosteroids
Glucocorticoid receptor modulators
GRTooltip Glucocorticoid receptor
Agonists
Mixed
(SEGRMsTooltip Selective glucocorticoid receptor agonists)
Antagonists
Others
See also
Receptor/signaling modulators
Glucocorticoids and antiglucocorticoids
Mineralocorticoid receptor modulators
List of corticosteroids


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