| gamma-guanidinobutyraldehyde dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.2.1.54 | ||||||||
| CAS no. | 56831-75-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a gamma-guanidinobutyraldehyde dehydrogenase (EC 1.2.1.54) is an enzyme that catalyzes the chemical reaction
- 4-guanidinobutanal + NAD + H2O 4-guanidinobutanoate + NADH + 2 H
4-guanidinobutanoate + NADH + 2 HThe 3 substrates of this enzyme are 4-guanidinobutanal, NAD, and H2O, whereas its 3 products are 4-guanidinobutanoate, NADH, and H.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 4-guanidinobutanal:NAD+ 1-oxidoreductase. Other names in common use include alpha-guanidinobutyraldehyde dehydrogenase, 4-guanidinobutyraldehyde dehydrogenase, and GBAL dehydrogenase. This enzyme participates in urea cycle and metabolism of amino groups.
References
- Yorifuji T, Koike K, Sakurai T, Yokoyama K (1986). "4-Aminobutyraldehyde and 4-guanidinobutyraldehyde dehydrogenases for arginine degradation in Pseudomonas putida". Agric. Biol. Chem. 50 (8): 2009–2016. doi:10.1271/bbb1961.50.2009.
| Aldehyde/oxo oxidoreductases (EC 1.2) | |
|---|---|
| 1.2.1: NAD or NADP | |
| 1.2.2: cytochrome | |
| 1.2.3: oxygen | |
| 1.2.4: disulfide | |
| 1.2.7: iron–sulfur protein | |
| Enzymes | |
|---|---|
| Activity | |
| Regulation | |
| Classification | |
| Kinetics | |
| Types |
|
This EC 1.2 enzyme-related article is a stub. You can help Misplaced Pages by expanding it. |