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Hexafluronium bromide

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(Redirected from Hexafluronium) Pharmaceutical drug Pharmaceutical compound
Hexafluronium
Clinical data
ATC code
Identifiers
IUPAC name
  • N,N-di-9H-fluoren-9-yl-N,N,N',N'-tetramethylhexane-1,6-diaminium dibromide
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.005.697 Edit this at Wikidata
Chemical and physical data
FormulaC36H42Br2N2
Molar mass662.554 g·mol
3D model (JSmol)
SMILES
  • ..c1cccc3c1c2c(cccc2)C3(CCCCCC(C6c4ccccc4c5ccccc56)(C)C)(C)C
InChI
  • InChI=1S/C36H42N2.2BrH/c1-37(2,35-31-21-11-7-17-27(31)28-18-8-12-22-32(28)35)25-15-5-6-16-26-38(3,4)36-33-23-13-9-19-29(33)30-20-10-14-24-34(30)36;;/h7-14,17-24,35-36H,5-6,15-16,25-26H2,1-4H3;2*1H/q+2;;/p-2
  • Key:WDEFPRUEZRUYNW-UHFFFAOYSA-L
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Hexafluronium (or hexafluorenium) is a muscle relaxant. It acts as a nicotinic acetylcholine receptor antagonist.

References

  1. Baraka A (August 1975). "Hexafluorenium-suxamethonium interaction in patients with normal versus atypical cholinesterase". British Journal of Anaesthesia. 47 (8): 885–8. doi:10.1093/bja/47.8.885. PMID 1201167.
Skeletal muscle relaxants (M03)
Peripherally acting
(primarily antinicotinic,
NMJ block)
Non-depolarizing
Curare alkaloids
4° ammonium agents
Depolarizing
ACh release inhibitors
Centrally acting
Carbamic acid esters
Benzodiazepines
Nonbenzodiazepines
Thienodiazepines
Quinazolines
Anticholinergics
(Antimuscarinics)
Other
Directly acting
Nicotinic acetylcholine receptor modulators
nAChRsTooltip Nicotinic acetylcholine receptors
Agonists
(and PAMsTooltip positive allosteric modulators)
Antagonists
(and NAMsTooltip negative allosteric modulators)
Precursors
(and prodrugs)
See also
Receptor/signaling modulators
Muscarinic acetylcholine receptor modulators
Acetylcholine metabolism/transport modulators
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