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Inocoterone

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Chemical compound Pharmaceutical compound
Inocoterone
Clinical data
Other namesRU-29294; 2,5-Seco-A-dinorestr-9-en-17β-ol-5-one
Routes of
administration
Topical
Drug classNonsteroidal antiandrogen
Identifiers
IUPAC name
  • (3S,3aS,9aS,9bS)-6-Ethyl-3-hydroxy-3a-methyl-2,3,4,5,8,9,9a,9b-octahydro-1H-cyclopentanaphthalen-7-one
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC16H24O2
Molar mass248.366 g·mol
3D model (JSmol)
SMILES
  • CCC1=C2CCC3(C(C2CCC1=O)CCC3O)C
InChI
  • InChI=1S/C16H24O2/c1-3-10-11-8-9-16(2)13(5-7-15(16)18)12(11)4-6-14(10)17/h12-13,15,18H,3-9H2,1-2H3/t12-,13+,15+,16+/m1/s1
  • Key:DOTDLCMVUVGSDP-VRKREXBASA-N

Inocoterone (INNTooltip International Nonproprietary Name; developmental code name RU-29294) is a steroid-like nonsteroidal antiandrogen (NSAA) that was never marketed. An acetate ester, inocoterone acetate, shows greater antiandrogen activity and was developed, as a topical medication for the treatment of acne but showed only modest effectiveness in clinical trials and similarly was never marketed.

See also

References

  1. Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 686–. ISBN 978-1-4757-2085-3.
  2. Conn PM (23 July 2010). Techniques in Confocal Microscopy. Academic Press. pp. 215–. ISBN 978-0-12-384659-4.
  3. Annual Reports in Medicinal Chemistry. Academic Press. 2 September 1987. pp. 358–. ISBN 978-0-08-058366-2.
Androgen receptor modulators
ARTooltip Androgen receptor
Agonists
SARMsTooltip Selective androgen receptor modulator
Antagonists
GPRC6A
Agonists
See also
Receptor/signaling modulators
Androgens and antiandrogens
Estrogen receptor modulators
Progesterone receptor modulators
List of androgens and anabolic steroids


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