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Picloxydine

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Picloxydine
Names

IUPAC name 1-N',4-N'-bispiperazine-1,4-dicarboximidamide
Identifiers
CAS Number	5636-92-0
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL2104722
ChemSpider	64722
ECHA InfoCard	100.024.623
PubChem CID	71663
UNII	4YC2PY3AEU
CompTox Dashboard (EPA)	DTXSID50863586
InChI InChI=1S/C20H24Cl2N10/c21-13-1-5-15(6-2-13)27-17(23)29-19(25)31-9-11-32(12-10-31)20(26)30-18(24)28-16-7-3-14(22)4-8-16/h1-8H,9-12H2,(H4,23,25,27,29)(H4,24,26,28,30)Key: YNCLPFSAZFGQCD-UHFFFAOYSA-N InChI=1/C20H24Cl2N10/c21-13-1-5-15(6-2-13)27-17(23)29-19(25)31-9-11-32(12-10-31)20(26)30-18(24)28-16-7-3-14(22)4-8-16/h1-8H,9-12H2,(H4,23,25,27,29)(H4,24,26,28,30)Key: YNCLPFSAZFGQCD-UHFFFAOYAM
SMILES C1CN(CCN1C(=NC(=NC2=CC=C(C=C2)Cl)N)N)C(=NC(=NC3=CC=C(C=C3)Cl)N)N
Properties
Chemical formula	C₂₀H₂₄Cl₂N₁₀
Molar mass	475.37756
Pharmacology
ATC code	S01AX16 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). N verify (what is ?) Infobox references

Chemical compound

Picloxydine (trade name Vitabact) is a bisbiguanide antiseptic used in eye drops. It is structurally similar to chlorhexidine.

References

Obikili AG, Oji EO, Shonekan RO, Otti P (1988). "A double-blind comparison of picloxydine dihydrochloride (Vitabact eye drops) and sulfacetamide eye drops in the topical therapy of trachoma". Revue Internationale du Trachome et de Pathologie Oculaire Tropicale et Subtropicale et de Santé Publique. 65 (3–4): 119–32. PMID 3274675.

v t e Ophthalmologicals: anti-infectives (S01A)
Antibiotics	amphenicols (Chloramphenicol Azidamfenicol) tetracyclines (Tetracycline Chlortetracycline Oxytetracycline) aminoglycosides (Dihydrostreptomycin Neomycin Framycetin Kanamycin Amikacin Tobramycin Gentamicin Netilmicin Micronomicin) macrolides (Erythromycin Natamycin) beta-lactams (Ampicillin Benzylpenicillin) polypeptides (Polymyxin B Tyrothricin) Rifamycin Fusidic acid
Sulfonamides	Sulfacetamide Sulfadicramide Sulfafenazol Sulfafurazole Sulfamethizole
Antivirals	Aciclovir Famciclovir Fomivirsen Ganciclovir Idoxuridine Interferon Trifluridine Vidarabine
Fluoroquinolones	Besifloxacin Ciprofloxacin Gatifloxacin Levofloxacin (+dexamethasone) Lomefloxacin Moxifloxacin Norfloxacin Ofloxacin Tosufloxacin
Other	Bibrocathol Chlorhexidine Dibrompropamidine Hexamidine Nitrofural Picloxydine Polihexanide Povidone-iodine Propamidine Resorcinol Sodium borate Sodium propionate

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