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Micronomicin

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Chemical compound Pharmaceutical compound
Micronomicin
Clinical data
Other names(2R,3R,4R,5R)-2-oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-methylaminooxane-3,5-diol
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Eye drops, IV
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
IUPAC name
  • (1R,2S,3S,4R,6S)-4,6-diamino-3-{oxy}-2-hydroxycyclohexyl 2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-α-D-erythro-hexopyranoside
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC20H41N5O7
Molar mass463.576 g·mol
3D model (JSmol)
Melting point260 °C (500 °F) (dec.)
SMILES
  • C1(CO((1NC)O)O2(C(C(2O)O3(CC(O3)CNC)N)N)N)O
InChI
  • InChI=1S/C20H41N5O7/c1-20(28)8-29-19(14(27)17(20)25-3)32-16-12(23)6-11(22)15(13(16)26)31-18-10(21)5-4-9(30-18)7-24-2/h9-19,24-28H,4-8,21-23H2,1-3H3/t9-,10+,11-,12+,13-,14+,15+,16-,17+,18+,19+,20-/m0/s1
  • Key:DNYGXMICFMACRA-XHEDQWPISA-N
  (verify)

Micronomicin (INN) is an aminoglycoside antibiotic for use on the eye.

References

  1. Odakura Y, Kase H, Nakayama K (February 1983). "Sagamicin and the related aminoglycosides: fermentation and biosynthesis. III. Isolation and characterization of Micromonospora sagamiensis mutants blocked in gentamicin C1 pathway". The Journal of Antibiotics. 36 (2): 125–30. doi:10.7164/antibiotics.36.125. PMID 6833127.
  2. Fukuda M, Sasaki K (April 2002). "". Nippon Ganka Gakkai Zasshi. 106 (4): 195–200. PMID 11979978.
Antibacterials that inhibit protein synthesis (J01A, J01B, J01F, J01G, QJ01XQ)
30S
Aminoglycosides
(initiation inhibitors)
-mycin (Streptomyces)
-micin (Micromonospora)
other
Tetracycline antibiotics
(tRNA binding)
Tetracyclines
Glycylcyclines
50S
Oxazolidinone
(initiation inhibitors)
Peptidyl transferase
Amphenicols
MLS (transpeptidation/translocation)
Macrolides
Ketolides
Lincosamides
Streptogramins
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