Names | |
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Preferred IUPAC name benzodioxol-5-yl]methyl (4-hydroxyphenyl)acetate | |
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CAS Number | |
3D model (JSmol) | |
ChEBI | |
ChemSpider | |
ECHA InfoCard | 100.165.094 |
MeSH | tinyatoxin |
PubChem CID | |
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CompTox Dashboard (EPA) | |
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Properties | |
Chemical formula | C36H38O8 |
Molar mass | 598.692 g·mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Y verify (what is ?) Infobox references |
Tinyatoxin | |
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Heat | Above peak |
Scoville scale | 5,300,000,000 SHU |
Tinyatoxin (TTX or TTN) is an analog of the neurotoxin resiniferatoxin. It occurs naturally in Euphorbia poissonii.
It is a neurotoxin that acts via full agonism of the vanilloid receptors of sensory nerves. Tinyatoxin has a potential for pharmaceutical uses similar to uses of capsaicin. Tinyatoxin is about one third as strong as resiniferatoxin but is still an ultrapotent analogue of capsaicin, with a heat intensity estimate of 300 to 350 times that of capsaicin.
References
- Euphorbia poissonii in BoDD – Botanical Dermatology Database
- Szallasi, A. & Blumberg, P.M. (1991). "Characterization of vanilloid receptors in the dorsal horn of pig spinal cord". Brain Res. 547 (2): 335–338. doi:10.1016/0006-8993(91)90982-2. PMID 1884211. S2CID 25052101.
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