Razobazam: Difference between revisions

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Revision as of 02:41, 10 August 2011 editCheMoBot (talk \| contribs)Bots141,565 edits Updating {{drugbox}} (changes to verified fields - updated 'ChemSpiderID_Ref', 'DrugBank_Ref', 'ChEMBL_Ref', 'ChEBI_Ref', 'KEGG_Ref', 'StdInChI_Ref', 'StdInChIKey_Ref', 'ChEBI_Ref') per [[Misplaced Pages:WikiProject Chemicals/Chembox validation\|Chem/Drugbo← Previous edit		Revision as of 05:17, 12 August 2011 edit undoCheMoBot (talk \| contribs)Bots141,565 edits Updating {{drugbox}} (no changed fields - added verified revid - updated 'ChemSpiderID_Ref', 'ChEMBL_Ref', 'ChEBI_Ref', 'KEGG_Ref', 'StdInChI_Ref', 'StdInChIKey_Ref', 'ChEBI_Ref') per [[Misplaced Pages:WikiProject Chemicals/Chembox validation\|Chem/DrugboxNext edit →
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		⚫	\| UNII_Ref = {{fdacite\|correct\|FDA}}
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	\| UNII = LZ84VWN0U4		\| UNII = LZ84VWN0U4
	\| verifiedrevid = ~~348274299~~		\| verifiedrevid = 443983722
	\| IUPAC_name = 3,8-dimethyl- 4-phenyl- 2,8-dihydropyrazolo diazepine- 5,7(4''H'',6''H'')- dione		\| IUPAC_name = 3,8-dimethyl- 4-phenyl- 2,8-dihydropyrazolo diazepine- 5,7(4''H'',6''H'')- dione
	\| image = Razobazam.svg		\| image = Razobazam.svg

Revision as of 05:17, 12 August 2011

Pharmaceutical compound

Razobazam
Clinical data

ATC code	none
Identifiers
IUPAC name 3,8-dimethyl- 4-phenyl- 2,8-dihydropyrazolo diazepine- 5,7(4H,6H)- dione
CAS Number	78466-98-5
PubChem CID	71228
UNII	LZ84VWN0U4
CompTox Dashboard (EPA)	DTXSID20868482
Chemical and physical data
Formula	C₁₄H₁₄N₄O₂
Molar mass	270.28 g/mol g·mol
3D model (JSmol)	Interactive image
SMILES CC1=C2C(=NN1)N(C(=O)CC(=O)N2C3=CC=CC=C3)C
(verify)

Razobazam (INN) is a drug which is a benzodiazepine derivative. Its mechanism of action appears to be quite different from that of most benzodiazepine drugs, and it produces nootropic effects in animal studies.

References

Hock FJ, Scheich H. Functional activity in the brain of socially deprivated rats produced by an active avoidance test after razobazam (Hoe 175) treatment: a 2-deoxyglucose study. Behavioural and Neural Biology. 1986 Nov;46(3):398-409. PMID 3814045

v t e Benzodiazepines
1,4-Benzodiazepines	2-Oxoquazepam 3-Hydroxyphenazepam Bromazepam BMS-906024* Camazepam Carburazepam Chlordiazepoxide Cinazepam Cinolazepam Clonazepam Cloniprazepam Clorazepate Cyprazepam Delorazepam Demoxepam Desmethylflunitrazepam Devazepide* Diazepam Diclazepam Difludiazepam Doxefazepam Elfazepam Ethyl carfluzepate Ethyl dirazepate Ethyl loflazepate Flubromazepam Fletazepam Fludiazepam Flunitrazepam Flurazepam Flutemazepam Flutoprazepam Fosazepam Gidazepam Halazepam Iclazepam Irazepine* Kenazepine Ketazolam Lorazepam Lormetazepam Lufuradom* Meclonazepam Medazepam Menitrazepam Metaclazepam Motrazepam N-Desalkylflurazepam Nifoxipam Nimetazepam Nitemazepam Nitrazepam Nitrazepate Nordazepam Nortetrazepam Oxazepam Phenazepam Pinazepam Pivoxazepam Prazepam Proflazepam Quazepam QH-II-66 Reclazepam RO4491533* Ro05-4082 Ro5-4864* Ro07-5220 Ro07-9749 Ro20-8065 Ro20-8552 SH-I-048A Sulazepam Temazepam Tetrazepam Tifluadom* Timelotem* Tolufazepam Triflunordazepam Tuclazepam Uldazepam
1,5-Benzodiazepines	Arfendazam Clobazam CP-1414S Lofendazam Triflubazam
2,3-Benzodiazepines*	Girisopam GYKI-52466 GYKI-52895 Nerisopam Talampanel Tofisopam
Triazolobenzodiazepines	Adinazolam Alprazolam Balovaptan* Bromazolam Clonazolam Estazolam Fluadinazolam Flualprazolam Flubromazolam Flunitrazolam Nitrazolam Phenazolam Pyrazolam Rilmazolam (active metabolite of Rilmazafone) Triazolam
Imidazobenzodiazepines	Bretazenil Climazolam EVT-201 FG-8205 Flumazenil GL-II-73 Imidazenil I-Iomazenil L-655,708 Loprazolam Midazolam PWZ-029 Remimazolam Ro15-4513 Ro48-6791 Ro48-8684 Ro4938581 Sarmazenil SH-053-R-CH3-2′F
Oxazolobenzodiazepines	Cloxazolam Flutazolam Haloxazolam Mexazolam Oxazolam
Thienodiazepines	Bentazepam Clotiazepam Ro09-9212
Thienotriazolodiazepines	α-Hydroxyetizolam Apafant* Brotizolam Ciclotizolam Clotizolam Deschloroclotizolam Deschloroetizolam Etizolam Flubrotizolam Fluclotizolam Fluetizolam Israpafant* JQ1* Metizolam
Thienobenzodiazepines*	Olanzapine Telenzepine
Pyridodiazepines	Lopirazepam
Pyridotriazolodiazepines	Zapizolam
Pyrazolodiazepines	Razobazam* Ripazepam Zolazepam Zomebazam Zometapine*
Pyrrolodiazepines	Premazepam
Tetrahydroisoquinobenzodiazepines	Clazolam
Pyrrolobenzodiazepines*	Anthramycin
Benzodiazepine prodrugs	Alprazolam triazolobenzophenone Avizafone Rilmazafone
* atypical activity profile (not GABA_A receptor ligands)

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Revision as of 05:17, 12 August 2011

See also

References