Diclofenamide: Difference between revisions

Revision as of 14:52, 15 November 2011 editBeetstra (talk \| contribs)Edit filter managers, Administrators172,031 edits Script assisted update of identifiers for the Chem/Drugbox validation project (updated: 'DrugBank').← Previous edit		Revision as of 14:52, 15 November 2011 edit undoBeetstra (talk \| contribs)Edit filter managers, Administrators172,031 edits Script assisted update of identifiers for the Chem/Drugbox validation project (updated: '').Next edit →
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	\| PubChem = 3038		\| PubChem = 3038
	\| DrugBank_Ref = {{drugbankcite\|correct\|drugbank}}		\| DrugBank_Ref = {{drugbankcite\|correct\|drugbank}}
	\| DrugBank = ~~DB07948~~		\| DrugBank = APRD00131
	\| ChemSpiderID_Ref = {{chemspidercite\|correct\|chemspider}}		\| ChemSpiderID_Ref = {{chemspidercite\|correct\|chemspider}}
	\| ChemSpiderID = 2930		\| ChemSpiderID = 2930

Revision as of 14:52, 15 November 2011

Pharmaceutical compound

Diclofenamide
Clinical data

AHFS/Drugs.com	International Drug Names
MedlinePlus	a601233
ATC code	S01EC02 (WHO)
Pharmacokinetic data
Protein binding	55%
Identifiers
IUPAC name 4,5-dichlorobenzene-1,3-disulfonamide
CAS Number	120-97-8
PubChem CID	3038
DrugBank	APRD00131
ChemSpider	2930
UNII	VVJ6673MHY
KEGG	D00518
ChEBI	CHEBI:101085
ChEMBL	ChEMBL17
CompTox Dashboard (EPA)	DTXSID1022922
ECHA InfoCard	100.004.037
Chemical and physical data
Formula	C₆H₆Cl₂N₂O₄S₂
Molar mass	305.16 g/mol g·mol
3D model (JSmol)	Interactive image
SMILES Clc1c(cc(cc1Cl)S(=O)(=O)N)S(=O)(=O)N
InChI InChI=1S/C6H6Cl2N2O4S2/c7-4-1-3(15(9,11)12)2-5(6(4)8)16(10,13)14/h1-2H,(H2,9,11,12)(H2,10,13,14) Key:GJQPMPFPNINLKP-UHFFFAOYSA-N
(verify)

Diclofenamide (or dichlorphenamide) is a sulfonamide and a carbonic anhydrase inhibitor of the meta-Disulfamoylbenzene class.

Tawil R, McDermott M, Brown R, Shapiro B, Ptacek L, McManis P, Dalakas M, Spector S, Mendell J, Hahn A, Griggs R (2000). "Randomized trials of dichlorphenamide in the periodic paralyses. Working Group on Periodic Paralysis". Ann Neurol. 47 (1): 46–53. doi:10.1002/1531-8249(200001)47:1<46::AID-ANA9>3.0.CO;2-H. PMID 10632100.{{cite journal}}: CS1 maint: multiple names: authors list (link)
Okada S, Izumi W, Murai M, Komatsu H, Ishimitsu S (1991). "". Eisei Shikenjo Hokoku. 109 (109): 148–50. PMID 1364383.{{cite journal}}: CS1 maint: multiple names: authors list (link)

Drugs used for glaucoma preparations and miosis (S01E)

muscarinic	Aceclidine Pilocarpine
muscarinic/nicotinic	Acetylcholine Carbachol
acetylcholinesterase inhibitors	Demecarium Ecothiopate Stigmine (Fluostigmine Neostigmine Physostigmine) Paraoxon

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