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Dupracetam: Difference between revisions

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'''Dupracetam''' is a ] drug from the ] family.<ref name="pmid7294979">{{cite journal |vauthors=Dell HD, Jacobi H, Kamp R, Kurz J, Wünsche C |title= |language=de |journal=Archiv der Pharmazie |volume=314 |issue=8 |pages=697–702 |date=August 1981 |pmid=7294979 |doi= 10.1002/ardp.19813140808|s2cid=95603731 }}</ref><ref name="pmid2829047">{{cite journal |vauthors=Hall ED, Von Voigtlander PF |title=Facilitatory effects of piracetam on excitability of motor nerve terminals and neuromuscular transmission |journal=Neuropharmacology |volume=26 |issue=11 |pages=1573–9 |date=November 1987 |pmid=2829047 |doi= 10.1016/0028-3908(87)90003-7|s2cid=7759558 }}</ref> '''Dupracetam''' is a ] drug from the ] family.<ref name="pmid7294979">{{cite journal | vauthors = Dell HD, Jacobi H, Kamp R, Kurz J, Wünsche C | title = | language = de | journal = Archiv der Pharmazie | volume = 314 | issue = 8 | pages = 697–702 | date = August 1981 | pmid = 7294979 | doi = 10.1002/ardp.19813140808 | s2cid = 95603731 }}</ref><ref name="pmid2829047">{{cite journal | vauthors = Hall ED, Von Voigtlander PF | title = Facilitatory effects of piracetam on excitability of motor nerve terminals and neuromuscular transmission | journal = Neuropharmacology | volume = 26 | issue = 11 | pages = 1573–1579 | date = November 1987 | pmid = 2829047 | doi = 10.1016/0028-3908(87)90003-7 | s2cid = 7759558 }}</ref>


One of its metabolites, 1-Methylhydantoin, displays renal toxicity in high doses.<ref>{{Cite journal One of its metabolites, 1-Methylhydantoin, displays renal toxicity in high doses.<ref>{{cite journal | vauthors = Yang B, Liu D, Li CZ, Liu FY, Peng YM, Jiang YS | title = 1-Methylhydantoin cytotoxicity on renal proximal tubular cells in vitro | journal = Renal Failure | volume = 29 | issue = 8 | pages = 1025–1029 | year = 2007 | pmid = 18067051 | doi = 10.1080/08860220701641272 | s2cid = 26843776 }}</ref>
| last1 = Yang | first1 = B.
| last2 = Liu | first2 = D.
| last3 = Li | first3 = C.
| last4 = Liu | first4 = F.
| last5 = Peng | first5 = Y.
| last6 = Jiang | first6 = Y.
| doi = 10.1080/08860220701641272
| title = 1-Methylhydantoin Cytotoxicity on Renal Proximal Tubular Cells in Vitro
| journal = Renal Failure
| volume = 29
| issue = 8
| pages = 1025–1029
| year = 2007
| pmid = 18067051
| s2cid = 26843776
}}</ref>


==See also== == See also ==
* ] * ]


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] ]
] ]



{{nervous-system-drug-stub}} {{nervous-system-drug-stub}}

Revision as of 20:07, 29 October 2023

Chemical compound Pharmaceutical compound
Dupracetam
Clinical data
ATC code
  • none
Legal status
Legal status
  • In general: unscheduled
Identifiers
IUPAC name
  • 2-(2-oxopyrrolidin-1-yl)-N'-acetohydrazide
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.056.279 Edit this at Wikidata
Chemical and physical data
FormulaC12H18N4O4
Molar mass282.300 g·mol
3D model (JSmol)
SMILES
  • C1CC(=O)N(C1)CC(=O)NNC(=O)CN2CCCC2=O
InChI
  • InChI=1S/C12H18N4O4/c17-9(7-15-5-1-3-11(15)19)13-14-10(18)8-16-6-2-4-12(16)20/h1-8H2,(H,13,17)(H,14,18)
  • Key:YPUPYVWSTBYCBY-UHFFFAOYSA-N
  (what is this?)  (verify)

Dupracetam is a nootropic drug from the racetam family.

One of its metabolites, 1-Methylhydantoin, displays renal toxicity in high doses.

See also

References

  1. Dell HD, Jacobi H, Kamp R, Kurz J, Wünsche C (August 1981). "". Archiv der Pharmazie (in German). 314 (8): 697–702. doi:10.1002/ardp.19813140808. PMID 7294979. S2CID 95603731.
  2. Hall ED, Von Voigtlander PF (November 1987). "Facilitatory effects of piracetam on excitability of motor nerve terminals and neuromuscular transmission". Neuropharmacology. 26 (11): 1573–1579. doi:10.1016/0028-3908(87)90003-7. PMID 2829047. S2CID 7759558.
  3. Yang B, Liu D, Li CZ, Liu FY, Peng YM, Jiang YS (2007). "1-Methylhydantoin cytotoxicity on renal proximal tubular cells in vitro". Renal Failure. 29 (8): 1025–1029. doi:10.1080/08860220701641272. PMID 18067051. S2CID 26843776.
Racetams
Racetams
Phenylpiracetams
Racetam-like
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