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Identifiers | |
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IUPAC name
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CAS Number | |
PubChem CID | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.116.767 |
Chemical and physical data | |
Formula | C29H33FN2O4 |
Molar mass | 492.58 g/mol g·mol |
SCH-530,348 is a thrombin receptor (PAR-1) antagonist based on the natural product himbacine. Developed by Schering-Plough, SCH-530,348 is a potential treatment for acute coronary syndrome chest pain caused by coronary artery disease.
Now owned by Merck, this compound is being called Vorapaxar.
References
- Samuel Chackalamannil (2008). "Discovery of a Novel, Orally Active Himbacine-Based Thrombin Receptor Antagonist (SCH 530348) with Potent Antiplatelet Activity". Journal of Medicinal Chemistry. 51: 3061. doi:10.1021/jm800180e.
Antithrombotics (thrombolytics, anticoagulants and antiplatelet drugs) (B01) | |||||||||||||||
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Antiplatelet drugs |
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Anticoagulants |
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Thrombolytic drugs/ fibrinolytics | |||||||||||||||
Non-medicinal | |||||||||||||||
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