Ditazole - Misplaced Pages

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Ditazole
Clinical data

AHFS/Drugs.com	International Drug Names
ATC code	B01AC01 (WHO)
Identifiers
IUPAC name 2,2'-(4,5-Diphenyloxazol-2-ylazanediyl)diethanol
CAS Number	18471-20-0
PubChem CID	29088
DrugBank	DB08994
ChemSpider	27061
UNII	H2BQI5Z8FT
KEGG	D07138
CompTox Dashboard (EPA)	DTXSID3022954
ECHA InfoCard	100.038.488
Chemical and physical data
Formula	C₁₉H₂₀N₂O₃
Molar mass	324.380 g·mol
3D model (JSmol)	Interactive image
SMILES C1=CC=C(C=C1)C2=C(OC(=N2)N(CCO)CCO)C3=CC=CC=C3
InChI InChI=1S/C19H20N2O3/c22-13-11-21(12-14-23)19-20-17(15-7-3-1-4-8-15)18(24-19)16-9-5-2-6-10-16/h1-10,22-23H,11-14H2 Key:UUCMDZWCRNZCOY-UHFFFAOYSA-N
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Ditazole is a non-steroidal anti-inflammatory agent with analgesic and antipyretic activity similar to phenylbutazone. It is also a platelet aggregation inhibitor which is marketed in Spain and Portugal under the trade name Ageroplas.

References

"Ditazole". PubChem. U.S. National Library of Medicine.
Budavari S, O'Neil M, Smith A, Heckelman P, Obenchain J (1996). The Merck index : an encyclopedia of chemicals, drugs, and biologicals (12th ed.). Whitehouse Station, NJ: Merck. ISBN 978-0-911910-12-4. 3432.

Antithrombotics (thrombolytics, anticoagulants and antiplatelet drugs) (B01)

Antiplatelet drugs

Glycoprotein IIb/IIIa inhibitors	Abciximab Eptifibatide Orbofiban Roxifiban Sibrafiban Tirofiban
ADP receptor/P2Y₁₂ inhibitors	Thienopyridines Clopidogrel Prasugrel Ticlopidine Nucleotide/nucleoside analogs Cangrelor Elinogrel Ticagrelor
Prostaglandin analogue (PGI2)	Beraprost Iloprost Prostacyclin Treprostinil
COX inhibitors	Acetylsalicylic acid/Aspirin Aloxiprin Carbasalate calcium Indobufen Triflusal
Thromboxane inhibitors	Thromboxane synthase inhibitors Dipyridamole (+ aspirin) Picotamide Terbogrel Receptor antagonists Terbogrel Terutroban
Phosphodiesterase inhibitors	Cilostazol Dipyridamole Triflusal
Other	Cloricromen Ditazole Vorapaxar

Anticoagulants

Vitamin K antagonists
(inhibit II, VII, IX, X)

Factor Xa inhibitors
(with some II inhibition)

Heparin group/ glycosaminoglycans/ (bind antithrombin)	Low-molecular-weight heparin Bemiparin Certoparin Dalteparin Enoxaparin Nadroparin Parnaparin Reviparin Tinzaparin Oligosaccharides Fondaparinux Idraparinux Heparinoids Danaparoid Dermatan sulfate Sulodexide
Direct Xa inhibitors ("xabans")	Apixaban Betrixaban Darexaban Edoxaban Otamixaban Rivaroxaban

Direct thrombin (IIa) inhibitors

Other

Thrombolytic drugs/
fibrinolytics

Non-medicinal

WHO-EM
Withdrawn from market
Clinical trials:
- Phase III
- Never to phase III

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