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Oxolamine

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This is the current revision of this page, as edited by MRTFR55 (talk | contribs) at 10:59, 28 December 2023 (Rescuing 3 sources and tagging 0 as dead.) #IABot (v2.0.9.5). The present address (URL) is a permanent link to this version.

Revision as of 10:59, 28 December 2023 by MRTFR55 (talk | contribs) (Rescuing 3 sources and tagging 0 as dead.) #IABot (v2.0.9.5)(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff) Cough suppressant Pharmaceutical compound
Oxolamine
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
IUPAC name
  • N,N-diethyl-2-(3-phenyl-1,2,4-oxadiazol-5-yl)ethanamine
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.012.267 Edit this at Wikidata
Chemical and physical data
FormulaC14H19N3O
Molar mass245.326 g·mol
3D model (JSmol)
SMILES
  • n1c(onc1c2ccccc2)CCN(CC)CC
InChI
  • InChI=1S/C14H19N3O/c1-3-17(4-2)11-10-13-15-14(16-18-13)12-8-6-5-7-9-12/h5-9H,3-4,10-11H2,1-2H3
  • Key:IDCHQQSVJAAUQQ-UHFFFAOYSA-N
  (what is this?)  (verify)

Oxolamine is a cough suppressant that is available as a generic drug in many jurisdictions.

Oxolamine also has anti-inflammatory activity, which causes a reduction in irritation of the nerve receptors of the respiratory tract.

It is mainly used for the treatment of pharyngitis, tracheitis, bronchitis, bronchiectasis and pertussis.

Oxolamine is not approved in the USA, it may be marketed elsewhere internationally as a cough suppressant. It is listed as a prescription drug in New Zealand legislation. Oxolamine is also approved in Taiwan for the treatment of respiratory tract inflammation.

References

  1. de Groot AC (2022). "3.357 Oxolamine". Systemic Drugs. Monographs in Contact Allergy. Vol. 4 (First ed.). CRC Press. p. 712. ISBN 978-1-00-054991-1.
  2. "Oxolamine". drugs.com. 19 April 2015. Archived from the original on 20 September 2018. Retrieved 23 January 2018.
  3. ^ "NCATS Inxight Drugs — OXOLAMINE CITRATE". drugs.ncats.io. Archived from the original on 2022-09-26. Retrieved 2022-09-26.
  4. "Oxolamine". go.drugbank.com. Archived from the original on 2022-09-26. Retrieved 2022-09-26.
Cough and cold preparations (R05)
Expectorants
Mucolytics
Cough suppressants
Opium alkaloids,
opioids,
and derivatives
Other


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