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Cytidine triphosphate

Names
IUPAC name Cytidine 5′-(tetrahydrogen triphosphate)
Systematic IUPAC name O-{methyl} tetrahydrogen triphosphate
Other names CTP; Cytidine-5'-triphosphate
Identifiers
CAS Number	65-47-4
3D model (JSmol)	Interactive image Interactive image
ChemSpider	19952488
ECHA InfoCard	100.000.556
IUPHAR/BPS	1741
MeSH	Cytidine+triphosphate
PubChem CID	6176
UNII	K0118UX80T
CompTox Dashboard (EPA)	DTXSID70889324
InChI InChI=1S/C9H13N3O5.3H3O4P/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8;3*1-5(2,3)4/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16);3*(H3,1,2,3,4)/t4-,6-,7-,8-;;;/m1.../s1Key: NPIWPFUCEAMYFN-LLWADOMFSA-N InChI=1/C9H16N3O14P3/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1Key: PCDQPRRSZKQHHS-XVFCMESIBL InChI=1/C9H13N3O5.3H3O4P/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8;3*1-5(2,3)4/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16);3*(H3,1,2,3,4)/t4-,6-,7-,8-;;;/m1.../s1Key: NPIWPFUCEAMYFN-LLWADOMFBY
SMILES c1cn(c(=O)nc1N)2(((O2)CO(=O)(O)O(=O)(O)OP(=O)(O)O)O)O OP(O)(=O)O.OP(O)(=O)O.OP(O)(=O)O.N/C1=N/C(=O)N(/C=C1)2O(CO)(O)2O
Properties
Chemical formula	C9H16N3O14P3
Molar mass	483.156
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Y verify (what is  ?) Infobox references

Cytidine triphosphate (CTP) is a pyrimidine nucleoside triphosphate. CTP, much like ATP, consists of a ribose sugar, and three phosphate groups. The major difference between the two molecules is the base used, which in CTP is cytosine.

CTP is a substrate in the synthesis of RNA.

CTP is a high-energy molecule similar to ATP, but its role as an energy coupler is limited to a much smaller subset of metabolic reactions. CTP is a coenzyme in metabolic reactions like the synthesis of glycerophospholipids, where it is used for activation and transfer of diacylglycerol and lipid head groups, and glycosylation of proteins.

CTP acts as an inhibitor of the enzyme aspartate carbamoyltransferase, which is used in pyrimidine biosynthesis.

See also

• CTP synthase
• Cytidine
• Cytosine
• Pyrimidine biosynthesis

References

1. Buchanan BB, Gruissem W, Jones RL (2000). Biochemistry & molecular biology of plants (1st ed.). American society of plant physiology. ISBN 978-0-943088-39-6.
2. Blackburn, G. Michael. Nucleic Acids in Chemistry and Biology. The Royal Society of Chemistry, 2006, p. 119-120.

• Nucleotides
• Phosphate esters
• Pyrimidones