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Dacuronium bromide

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(Redirected from Dacuronium) Chemical compound Pharmaceutical compound
Dacuronium bromide
Clinical data
Other namesNB-68; 17β-Hydroxypancuronium bromide; 3α-(Acetyloxy)-17β-hydroxy-2β,16β-bis(1-methylpiperidinium-1-yl)-5α-androstane dibromide; 2β,16β-Dipiperidino-5α-androstane-3α,17β-diol 3α-acetate dimethobromide
Identifiers
IUPAC name
  • phenanthren-3-yl] acetate;dibromide
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.043.834 Edit this at Wikidata
Chemical and physical data
FormulaC33H58Br2N2O3
Molar mass690.646 g·mol
3D model (JSmol)
SMILES
  • CC(=O)O1C2CC3(2(C14(CCCCC4)C)C)CC5(3C(5O)6(CCCCC6)C)C..
InChI
  • InChI=1S/C33H58N2O3.2BrH/c1-23(36)38-30-20-24-12-13-25-26(33(24,3)22-29(30)35(5)18-10-7-11-19-35)14-15-32(2)27(25)21-28(31(32)37)34(4)16-8-6-9-17-34;;/h24-31,37H,6-22H2,1-5H3;2*1H/q+2;;/p-2/t24-,25+,26-,27-,28-,29-,30-,31-,32-,33-;;/m0../s1
  • Key:SUKULMJPMHYWKC-GMMLHHOXSA-L

Dacuronium bromide (INN, BAN) (developmental code name NB-68) is an aminosteroid neuromuscular blocking agent which was never marketed. It acts as a competitive antagonist of the nicotinic acetylcholine receptor (nAChR).

References

  1. Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 647–. ISBN 978-1-4757-2085-3.
  2. ^ Morton IK, Hall JM (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 90–. ISBN 978-94-011-4439-1.
  3. Progress in Medicinal Chemistry. Elsevier. 1 January 1979. pp. 102–. ISBN 978-0-08-086264-4.
  4. Maclagan J (1976). "Competitive neuromuscular blocking drugs.". Neuromuscular Junction. Berlin, Heidelberg: Springer. pp. 421–486. ISBN 978-3-642-45476-9.
  5. Kharkevich DA (6 December 2012). New Neuromuscular Blocking Agents: Basic and Applied Aspects. Springer Science & Business Media. pp. 201–202, 213. ISBN 978-3-642-70682-0.


Skeletal muscle relaxants (M03)
Peripherally acting
(primarily antinicotinic,
NMJ block)
Non-depolarizing
Curare alkaloids
4° ammonium agents
Depolarizing
ACh release inhibitors
Centrally acting
Carbamic acid esters
Benzodiazepines
Nonbenzodiazepines
Thienodiazepines
Quinazolines
Anticholinergics
(Antimuscarinics)
Other
Directly acting
Nicotinic acetylcholine receptor modulators
nAChRsTooltip Nicotinic acetylcholine receptors
Agonists
(and PAMsTooltip positive allosteric modulators)
Antagonists
(and NAMsTooltip negative allosteric modulators)
Precursors
(and prodrugs)
See also
Receptor/signaling modulators
Muscarinic acetylcholine receptor modulators
Acetylcholine metabolism/transport modulators
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