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Ornithine translocase

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(Redirected from SLC25A15)
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
Identifiers
SymbolSLC25A15
Alt. symbolsORNT1, HHH
NCBI gene10166
HGNC10985
OMIM603861
RefSeqNM_014252
UniProtQ9Y619
Other data
LocusChr. 13 q14
Search for
StructuresSwiss-model
DomainsInterPro

Ornithine translocase is responsible for transporting ornithine from the cytosol into the mitochondria in the urea cycle. It is highly expressed in the liver and pancreas.

Pathology

A disorder is associated with ornithine translocase deficiency, and a form of hyperammonemia.

See also

External links

Membrane proteins, carrier proteins: membrane transport proteins solute carrier (TC 2A)
By group
SLC1–10
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SLC11–20
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SLC21–30
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SLC31–40
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SLC41–48
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SLCO1–4
Ion pumps
Symporter, Cotransporter
Antiporter (exchanger)
see also solute carrier disorders
Metabolism: amino acid metabolism - urea cycle enzymes
Main cycle
mitochondrial matrix:
cytosol:
Regulatory/transport


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