Misplaced Pages

Mitoguazone: Difference between revisions

Article snapshot taken from Wikipedia with creative commons attribution-sharealike license. Give it a read and then ask your questions in the chat. We can research this topic together.
Browse history interactively← Previous editNext edit →Content deleted Content addedVisualWikitext
Revision as of 17:46, 23 August 2021 editBoghog (talk | contribs)Autopatrolled, Extended confirmed users, IP block exemptions, New page reviewers, Pending changes reviewers, Rollbackers, Template editors137,805 edits consistent citation formatting← Previous edit Revision as of 00:44, 27 July 2022 edit undoJCW-CleanerBot (talk | contribs)Bots130,145 editsm task, replaced: Archiv Fur → Archiv fürTag: AWBNext edit →
Line 17: Line 17:
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> | legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_status = | legal_status =
| routes_of_administration = | routes_of_administration =


<!--Pharmacokinetic data--> <!--Pharmacokinetic data-->
Line 24: Line 24:
| metabolism = | metabolism =
| elimination_half-life = | elimination_half-life =
| excretion = | excretion =


<!--Identifiers--> <!--Identifiers-->
Line 53: Line 53:
}} }}


'''Mitoguazone''' (also known as methylglyoxal bis(guanylhydrazone) or MGBG) is a drug used in ].<ref name="pmid2655552">{{cite journal | vauthors = Hoffmann H, Gutsche W, Amlacher R, Schulze W, Werner W, Lenk H, Wohlrab W, Haupt E | title = | language = German | journal = Archiv Fur Geschwulstforschung | volume = 59 | issue = 2 | pages = 135–48 | date = 1989 | pmid = 2655552 | doi = | url = }}</ref> '''Mitoguazone''' (also known as methylglyoxal bis(guanylhydrazone) or MGBG) is a drug used in ].<ref name="pmid2655552">{{cite journal | vauthors = Hoffmann H, Gutsche W, Amlacher R, Schulze W, Werner W, Lenk H, Wohlrab W, Haupt E | title = | language = German | journal = Archiv für Geschwulstforschung | volume = 59 | issue = 2 | pages = 135–48 | date = 1989 | pmid = 2655552 | doi = | url = }}</ref>


== References == == References ==
Line 62: Line 62:
] ]
] ]



{{antineoplastic-drug-stub}} {{antineoplastic-drug-stub}}

Revision as of 00:44, 27 July 2022

Pharmaceutical compound
Mitoguazone
Clinical data
Other names2-amino]guanidine
ATC code
Identifiers
IUPAC name
  • (2E,2'E)-2,2'-(1E,2E)-propane-1,2-diylidenedihydrazinecarboximidamide
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
CompTox Dashboard (EPA)
ECHA InfoCard100.121.515 Edit this at Wikidata
Chemical and physical data
FormulaC5H12N8
Molar mass184.207 g·mol
3D model (JSmol)
SMILES
  • C\C(\C=N\NC(N)=N)=N/NC(N)=N
InChI
  • InChI=1S/C5H12N8/c1-3(11-13-5(8)9)2-10-12-4(6)7/h2H,1H3,(H4,6,7,12)(H4,8,9,13)/b10-2+,11-3+
  • Key:PKDBCJSWQUOKDO-UHFFFAOYSA-M
  (what is this?)  (verify)

Mitoguazone (also known as methylglyoxal bis(guanylhydrazone) or MGBG) is a drug used in chemotherapy.

References

  1. Hoffmann H, Gutsche W, Amlacher R, Schulze W, Werner W, Lenk H, Wohlrab W, Haupt E (1989). "". Archiv für Geschwulstforschung (in German). 59 (2): 135–48. PMID 2655552.
Intracellular chemotherapeutic agents / antineoplastic agents (L01)
SPs/MIs
(M phase)
Block microtubule assembly
Block microtubule disassembly
DNA replication
inhibitor
DNA precursors/
antimetabolites
(S phase)
Folic acid
Purine
Pyrimidine
Deoxyribonucleotide
Topoisomerase inhibitors
(S phase)
I
II
II+Intercalation
Crosslinking of DNA
(CCNS)
Alkylating
Platinum-based
Nonclassical
Intercalation
Photosensitizers/PDT
Other
Enzyme inhibitors
Receptor antagonists
Other/ungrouped


Stub icon

This antineoplastic or immunomodulatory drug article is a stub. You can help Misplaced Pages by expanding it.

Categories: