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'''Icariin''' is a ] classified as a ] ] ], a type of ]. It is the 8-prenyl derivative of ] 3,7-''O''-di]. The compound has been isolated from several species of plant belonging to the genus '']'' which are commonly known as horny goat weed, Yin Yang Huo,<ref>{{cite journal |vauthors=Liu JJ, Li SP, Wang YT |title=Optimization for quantitative determination of four flavonoids in Epimedium by capillary zone electrophoresis coupled with diode array detection using central composite design |journal=] |volume=1103 |issue=2 |pages=344–349 |year=2006 |pmid=16337210 |doi=10.1016/j.chroma.2005.11.036 }}</ref> and ''Herba epimedii''.<ref name="pmid22216122">{{cite journal |vauthors=Cai WJ, Huang JH, Zhang SQ, Wu B, Kapahi P, Zhang XM, Shen ZY| title=Icariin and its derivative icariside II extend healthspan via insulin/IGF-1 pathway in C. elegans | journal=PLOS ONE | volume=6 | issue=12 | year=2011 | page=e28835 | pmid=22216122 | pmc = 3244416 | doi-access=free | doi=10.1371/journal.pone.0028835 | veditors=Blagosklonny MV | bibcode=2011PLoSO...628835C }}</ref> Extracts from these plants are reputed to produce ] effects, and are used in ] to enhance erectile function.<ref>{{cite journal |vauthors=Makarova MN, Pozharitskaya ON, Shikov AN, Tesakova SV, Makarov VG, Tikhonov VP |title=Effect of lipid-based suspension of ''Epimedium koreanum Nakai'' extract on sexual behavior in rats |journal=] |volume=114 |issue=3 |pages=412–416 |year=2007 |pmid=17890032 |doi=10.1016/j.jep.2007.08.021 }}</ref> However, clinical trial data are lacking to support these claims.<ref>{{cite web|url=https://www.drugs.com/npp/horny-goat-weed.html|title=Horny Goat Weed|date=August 5, 2019|access-date=November 7, 2019|website=Drugs.com}}</ref><ref>{{Cite journal |last1=Fang |first1=Jian |last2=Zhang |first2=Yongjun |date=2017-10-12 |title=Icariin, an Anti-atherosclerotic Drug from Chinese Medicinal Herb Horny Goat Weed |journal=Frontiers in Pharmacology |volume=8 |pages=734 |doi=10.3389/fphar.2017.00734 |doi-access=free |issn=1663-9812 |pmc=5644024 |pmid=29075193}}</ref> |
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'''Icariin''' is a ] classified as a ] ] ], a type of ]. It is the 8-prenyl derivative of ] 3,7-''O''-di]. The compound has been isolated from several species of plant belonging to the genus '']'' which are commonly known as horny goat weed, Yin Yang Huo,<ref>{{cite journal |vauthors=Liu JJ, Li SP, Wang YT |title=Optimization for quantitative determination of four flavonoids in Epimedium by capillary zone electrophoresis coupled with diode array detection using central composite design |journal=] |volume=1103 |issue=2 |pages=344–349 |year=2006 |pmid=16337210 |doi=10.1016/j.chroma.2005.11.036 }}</ref> and ''Herba epimedii''.<ref name="pmid22216122">{{cite journal |vauthors=Cai WJ, Huang JH, Zhang SQ, Wu B, Kapahi P, Zhang XM, Shen ZY| title=Icariin and its derivative icariside II extend healthspan via insulin/IGF-1 pathway in C. elegans | journal=PLOS ONE | volume=6 | issue=12 | year=2011 | page=e28835 | pmid=22216122 | pmc = 3244416 | doi-access=free | doi=10.1371/journal.pone.0028835 | veditors=Blagosklonny MV | bibcode=2011PLoSO...628835C }}</ref> Extracts from these plants produce ] effects, and are used in ] to enhance erectile function.<ref>{{cite journal |vauthors=Makarova MN, Pozharitskaya ON, Shikov AN, Tesakova SV, Makarov VG, Tikhonov VP |title=Effect of lipid-based suspension of ''Epimedium koreanum Nakai'' extract on sexual behavior in rats |journal=] |volume=114 |issue=3 |pages=412–416 |year=2007 |pmid=17890032 |doi=10.1016/j.jep.2007.08.021 }}</ref> However, clinical trial data are lacking to support these claims.<ref>{{cite web|url=https://www.drugs.com/npp/horny-goat-weed.html|title=Horny Goat Weed|date=August 5, 2019|access-date=November 7, 2019|website=Drugs.com}}</ref><ref>{{Cite journal |last1=Fang |first1=Jian |last2=Zhang |first2=Yongjun |date=2017-10-12 |title=Icariin, an Anti-atherosclerotic Drug from Chinese Medicinal Herb Horny Goat Weed |journal=Frontiers in Pharmacology |volume=8 |pages=734 |doi=10.3389/fphar.2017.00734 |doi-access=free |issn=1663-9812 |pmc=5644024 |pmid=29075193}}</ref> |
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