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Benzethidine: Difference between revisions

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{{Opioids}}


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Revision as of 16:49, 26 May 2012

Pharmaceutical compound
Benzethidine
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
IUPAC name
  • ethyl 1-- 4-phenylpiperidine- 4-carboxylate
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC23H29NO3
Molar mass367.481 g/mol g·mol
3D model (JSmol)
SMILES
  • O=C(OCC)C3(c1ccccc1)CCN(CCOCc2ccccc2)CC3
InChI
  • InChI=1S/C23H29NO3/c1-2-27-22(25)23(21-11-7-4-8-12-21)13-15-24(16-14-23)17-18-26-19-20-9-5-3-6-10-20/h3-12H,2,13-19H2,1H3
  • Key:UVTBZAWTRVBTMK-UHFFFAOYSA-N
  (verify)

Benzethidine is a 4-phenylpiperidine derivative that is related to the opioid analgesic drug pethidine (meperidine, or Demerol).

Benzethidine is not currently used in medicine and is a Class A/Schedule I drug which is controlled under UN drug conventions. It has similar effects to other opioid derivatives, such as analgesia, sedation, nausea and respiratory depression.

References

  1. Maul C, Buschmann H, Sundermann B. Opioids: 3.3 Synthetic Opioids. Analgesics 2005; 159-169. ISBN 978-3-527-30403-5
  2. Cahal DA, Dare JG, Keith D. A Sequential Trial of Analgesics in Labour. International Journal of Obstetrics and Gynaecology 1961; 68(1): 88–93.

UNODC Bulletin on Narcotics 1961


Opioid receptor modulators
μ-opioid
(MOR)
Agonists
(abridged;
full list)
Antagonists
δ-opioid
(DOR)
Agonists
Antagonists
κ-opioid
(KOR)
Agonists
Antagonists
Nociceptin
(NOP)
Agonists
Antagonists
Others
  • Others: Kyotorphin (met-enkephalin releaser/degradation stabilizer)
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