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Revision as of 13:15, 21 October 2011 editBeetstra (talk | contribs)Edit filter managers, Administrators172,031 edits Script assisted update of identifiers for the Chem/Drugbox validation project (updated: '').← Previous edit Revision as of 13:25, 21 October 2011 edit undoCheMoBot (talk | contribs)Bots141,565 edits Updating {{drugbox}} (changes to verified fields - added verified revid - updated 'ChemSpiderID_Ref', 'UNII_Ref', 'ChEMBL_Ref', 'ChEBI_Ref', 'StdInChI_Ref', 'StdInChIKey_Ref', 'CAS_number_Ref') per Chem/Drugbox validation (report ...Next edit →
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| CAS_number = 156227-98-4 | CAS_number = 156227-98-4
| ATC_prefix = L04 | ATC_prefix = L04
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| ChemSpiderID = NA | ChemSpiderID = NA



Revision as of 13:25, 21 October 2011

Pharmaceutical compound
Afelimomab
Monoclonal antibody
TypeF(ab')2 fragment
SourceMouse
TargetTNFα
Clinical data
ATC code
Identifiers
CAS Number
ChemSpider
KEGG
  (what is this?)  (verify)

Afelimomab (MAK 195F) is an anti-TNFα monoclonal antibody. Administration of afelimomab reduces the concentration of interleukin-6 in patients with sepsis, but reduces mortality only marginally.

References

  1. PMID 16277704
  2. PMID 15640628
Immunosuppressive drugs / Immunosuppressants (L04)
Intracellular
(initiation)
Antimetabolites
Macrolides/
other IL-2 inhibitors
IMiDs
Intracellular
(reception)
IL-1 receptor antagonists
mTOR
Extracellular
Antibodies
Monoclonal
Serum target
(noncellular)
Cellular
target
Unsorted
Polyclonal
-cept (Fusion)
Unsorted
Monoclonal antibodies for the immune system
Immune system
Human
Mouse
Chimeric
Humanized

Immune activation: Dostarlimab
Other: Ibalizumab

Chimeric + humanized
Interleukin
Human
Humanized
Veterinary
Inflammatory lesions
Mouse


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