Propylketobemidone - Misplaced Pages

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Revision as of 05:31, 2 September 2011 by CheMoBot (talk | contribs) (Updating {{drugbox}} (no changed fields - updated 'DrugBank_Ref', 'UNII_Ref', 'ChEMBL_Ref', 'ChEBI_Ref', 'KEGG_Ref', 'ChEBI_Ref') per Chem/Drugbox validation (report errors or [[user talk:C)(diff) ← Previous revision | Latest revision (diff) | Newer revision → (diff) Pharmaceutical compound

Propylketobemidone
Clinical data

ATC code	none
Identifiers
IUPAC name 1-butan-1-one
ChemSpider	21106370
CompTox Dashboard (EPA)	DTXSID80903626
Chemical and physical data
Formula	C₁₆H₂₃NO₂
Molar mass	261.37 g/mol g·mol
3D model (JSmol)	Interactive image
SMILES O=C(CCC)C1(CCN(C)CC1)c2cccc(O)c2
InChI InChI=1S/C16H23NO2/c1-3-5-15(19)16(8-10-17(2)11-9-16)13-6-4-7-14(18)12-13/h4,6-7,12,18H,3,5,8-11H2,1-2H3 Key:VQISXVAQCJSTNS-UHFFFAOYSA-N
(verify)

Propylketobemidone is an opioid analgesic that is an analogue of ketobemidone. It was developed in the 1950s during research into analogues of pethidine and was assessed by the United Nations Office on Drugs and Crime but was not included on the list of drugs under international control, probably because it was not used in medicine or widely available.

Propylketobemidone is so named because it is the propyl ketone analogue of bemidone (hydroxypethidine). The more commonly used ethyl ketone ("ethylketobemidone") is simply called ketobemidone, as it is the only drug of this family to have been marketed.

Presumably propylketobemidone produces similar effects to ketobemidone and other opioids, such as analgesia and sedation, along with side effects such as nausea, itching, vomiting and respiratory depression which may be harmful or fatal.