Aurotioprol - Misplaced Pages

Chemical compound Pharmaceutical compound

Aurotioprol
Clinical data

AHFS/Drugs.com	International Drug Names
Routes of administration	Intramuscular injection
ATC code	M01CB05 (WHO)
Identifiers
IUPAC name Sodium aurothiopropanolsulfonate
CAS Number	27279-43-2
PubChem CID	44144564
ChemSpider	8628381
UNII	G7097J63E9
CompTox Dashboard (EPA)	DTXSID60912312
ECHA InfoCard	100.043.971
Chemical and physical data
Formula	C₃H₆AuNaO₄S₂
Molar mass	390.15 g·mol
3D model (JSmol)	Interactive image
SMILES C(C(CS(=O)(=O))O)..
InChI InChI=1S/C3H8O4S2.Au.Na/c4-3(1-8)2-9(5,6)7;;/h3-4,8H,1-2H2,(H,5,6,7);;/q;2*+1/p-2 Key:KBWWFTIQBJUOQR-UHFFFAOYSA-L
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Aurotioprol is a gold salt used as an antirheumatic agent.

References

Perrier P, Raffoux C, Thomas P, Tamisier JN, Busson M, Gaucher A, Streiff F (September 1985). "HLA antigens and toxic reactions to sodium aurothiopropanol sulphonate and D-penicillamine in patients with rheumatoid arthritis". Annals of the Rheumatic Diseases. 44 (9): 621–4. doi:10.1136/ard.44.9.621. PMC 1001721. PMID 3876081.
Veys EM, Mielants H, Verbruggen G (1987). "Goldsalts, levamisole and D-penicillamine as first choice slow-acting antirheumatic drugs in rheumatoid arthritis--a long-term follow-up study". Clinical and Experimental Rheumatology. 5 (2): 111–6. PMID 3608266.

v t e Specific antirheumatic products / DMARDs (M01C)
Quinolines	Oxycinchophen
Gold preparations	Sodium aurothiomalate Sodium aurothiosulfate Auranofin Aurothioglucose Aurotioprol
Other	Penicillamine #/Bucillamine Chloroquine #/Hydroxychloroquine Leflunomide Sulfasalazine # antifolate (Methotrexate #) thiopurine (Azathioprine) #
WHO-EM Withdrawn from market Clinical trials: Phase III Never to phase III

Gold(-I)

Gold(I)

Organogold(I) compounds	(AuC₆H₂(CH₃)₃)₅ (C₂H₅)₃PAuSC₅H₅O(CO₂CH₃)₃CH₂OCOCH₃ AuSC₅H₅O(OH)₃CH₂OH NaAuSCH₂CHOHCH₂SO₃ BrAuSC₄H₈ ClAuSC₄H₈ ClAuS(CH₃)₂ ClAuP(C₆H₅)₃ Na₂AuSCHCO₂CH₂CO₂ NaAuSCHCO₂CH₂CO₂H

Gold(II)

Gold(I,III)

Gold(III)

Aurates(III)	HAuCl₄ NaAuCl₄ HAuBr₄ HAu(NO₃)₄ ClO₂Au(ClO₄)₄ NaAuO₂

Gold(V)

Gold(VI)

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