Clonitazene - Misplaced Pages

Opioid analgesic Pharmaceutical compound

Clonitazene
Clinical data


Other names	Clonitazene
ATC code	none
Legal status
Legal status	BR: Class A1 (Narcotic drugs) CA: Schedule I DE: Anlage I (Authorized scientific use only) UK: Class A US: Schedule I
Identifiers
IUPAC name 2--5-nitrobenzimidazol-1-yl]-N,N-diethylethanamine
CAS Number	3861-76-5
PubChem CID	62528
DrugBank	DB01523
ChemSpider	56301
UNII	S90R21A2V2
KEGG	D12668
ChEMBL	ChEMBL2104616
CompTox Dashboard (EPA)	DTXSID90191931
Chemical and physical data
Formula	C₂₀H₂₃ClN₄O₂
Molar mass	386.88 g·mol
3D model (JSmol)	Interactive image
SMILES (=O)c3ccc1c(nc(n1CCN(CC)CC)Cc2ccc(Cl)cc2)c3
InChI InChI=1S/C20H23ClN4O2/c1-3-23(4-2)11-12-24-19-10-9-17(25(26)27)14-18(19)22-20(24)13-15-5-7-16(21)8-6-15/h5-10,14H,3-4,11-13H2,1-2H3 Key:GPZLDQAEBHTMPG-UHFFFAOYSA-N
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Clonitazene is an opioid analgesic of approximately three times the potency of morphine. It is related to etonitazene, an opioid of significantly higher potency. Clonitazene is not currently marketed. It is a controlled substance; in the United States it is a Schedule I Narcotic controlled substance with a DEA ACSCN of 9612 and an established manufacturing quota of 25 grams for 2022.

References

Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
Hunger A, Kebrle J, Rossi A, Hoffmann K (October 1957). "[Synthesis of analgesically active benzimidazole derivatives with basic substitutions]" [Synthesis of analgesically active benzimidazole derivatives with basic substitutions]. Experientia. 13 (10): 400–1. doi:10.1007/BF02161116. PMID 13473817. S2CID 32179439.