Danofloxacin - Misplaced Pages

Chemical compound Pharmaceutical compound

Danofloxacin
Clinical data

AHFS/Drugs.com	International Drug Names
ATCvet code	QJ01MA92 (WHO)
Identifiers
IUPAC name 1-Cyclopropyl-6-fluoro-7-heptan-6-yl]-4-oxoquinoline-3-carboxylic acid
CAS Number	112398-08-0
PubChem CID	71335
ChemSpider	64439
UNII	24CU1YS91D
ChEMBL	ChEMBL157548
CompTox Dashboard (EPA)	DTXSID0046432
ECHA InfoCard	100.166.385
Chemical and physical data
Formula	C₁₉H₂₀FN₃O₃
Molar mass	357.385 g·mol
3D model (JSmol)	Interactive image
SMILES O=C(O)\C4=C\N(c3cc(N1C2N(C)C1C2)c(F)cc3C4=O)C5CC5
InChI InChI=1S/C19H20FN3O3/c1-21-7-12-4-11(21)8-22(12)17-6-16-13(5-15(17)20)18(24)14(19(25)26)9-23(16)10-2-3-10/h5-6,9-12H,2-4,7-8H2,1H3,(H,25,26)/t11-,12-/m0/s1 Key:QMLVECGLEOSESV-RYUDHWBXSA-N
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Danofloxacin is a fluoroquinolone antibiotic used in veterinary medicine.

References

Lees P, Shojaee Aliabadi F (April 2002). "Rational dosing of antimicrobial drugs: animals versus humans". International Journal of Antimicrobial Agents. 19 (4): 269–84. doi:10.1016/s0924-8579(02)00025-0. PMID 11978498.

Antifolates
(inhibit bacterial
purine metabolism,
thereby inhibiting
DNA and RNA
synthesis)

Short-acting	Sulfaisodimidine Sulfamethizole Sulfadimidine (Sulfamethazine, Sulfadimerazine, Sulfadimezine) Sulfapyridine (Sulfasalazine) Sulfafurazole (Acetyl sulfisoxazole) Sulfanilamide Prontosil Sulfathiazole (Phthalylsulfathiazole, Succinylsulfathiazole) Sulfathiourea
Intermediate-acting	Sulfamethoxazole Sulfadiazine Sulfamoxole
Long-acting	Sulfadimethoxine Sulfadoxine Sulfalene Sulfametomidine Sulfametoxydiazine Sulfamethoxypyridazine Sulfaperin Sulfamerazine Sulfaphenazole Sulfamazone
Other/ungrouped	Mafenide Sulfacetamide Sulfaclozine Sulfadicramide Sulfaguanidine Sulfametrole Sulfanitran

Combinations

Other DHPS inhibitors

Quinolones
(inhibit bacterial
topoisomerase
and/or DNA gyrase,
thereby inhibiting
DNA replication)

2nd generation	Ciprofloxacin Ofloxacin Enoxacin Fleroxacin Lomefloxacin Nadifloxacin/Levonadifloxacin/Alalevonadifloxacin Norfloxacin Pefloxacin Rufloxacin
3rd generation	Levofloxacin Balofloxacin Grepafloxacin Pazufloxacin Sparfloxacin Temafloxacin Tosufloxacin
4th generation	Besifloxacin Delafloxacin Gatifloxacin Finafloxacin Gemifloxacin Moxifloxacin Clinafloxacin Garenoxacin Prulifloxacin Sitafloxacin Trovafloxacin/Alatrofloxacin
Veterinary	Danofloxacin Difloxacin Enrofloxacin Ibafloxacin Marbofloxacin Orbifloxacin Pradofloxacin Sarafloxacin

Newer non-fluorinated

Related (DG)

Nitroimidazole derivatives	Secnidazole

RNA synthesis

Rifamycins/ RNA polymerase	Rifampicin Rifabutin Rifapentine Rifaximin Rifalazil
Lipiarmycins	Fidaxomicin

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