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Dioxaphetyl butyrate

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(Redirected from Dioxaphetyl Butyrate) Chemical compound Pharmaceutical compound
Dioxaphetyl butyrate
Clinical data
Other namesAmidalgon, Spasmoxal
Routes of
administration		Oral, Other ROA Unknown
ATC code
  • none
Legal status
Legal status
Identifiers
IUPAC name
  • Ethyl 4-morpholin-4-yl-2,2-di(phenyl)butanoate
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
ECHA InfoCard100.006.731 Edit this at Wikidata
Chemical and physical data
FormulaC22H27NO3
Molar mass353.462 g·mol
3D model (JSmol)
SMILES
  • CCOC(=O)C(CCN1CCOCC1)(c1ccccc1)c1ccccc1
InChI
  • InChI=1S/C22H27NO3/c1-2-26-21(24)22(19-9-5-3-6-10-19,20-11-7-4-8-12-20)13-14-23-15-17-25-18-16-23/h3-12H,2,13-18H2,1H3
  • Key:LQGIXNQCOXNCRP-UHFFFAOYSA-N
  (what is this?)  (verify)

Dioxaphetyl butyrate (INN; trade names Amidalgon, Spasmoxal) is an opioid analgesic which is a diphenylacetic acid derivative, related to other open-chain opioid drugs such as dextropropoxyphene, levacetylmethadol (LAAM), lefetamine and dimenoxadol.

It produces similar effects to other opioids, including dependence, euphoria, analgesia, sedation, constipation, dizziness and nausea.

In the United States it is a Schedule I Narcotic controlled substance with an ACSCN of 9621 and a 2013 annual aggregate manufacturing quota of zero.

References

  1. Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
  2. "Dioxaphetyl butyrate". PubChem. U.S. National Library of Medicine. Retrieved 2019-06-03.
  3. "Dioxaphetyl butyrate | C22H27NO3". ChemSpider. Retrieved 2019-06-03.
  4. "Dioxaphetyl butyrate". drugcentral.org. Retrieved 2019-06-03.
  5. "Misuse of Drugs Act : Legislative history · Part I Class A · Section 1(a): Explicitly named Class A substances". isomerdesign.com. Retrieved 2019-06-03.
Opioid receptor modulators
μ-opioid
(MOR)
Agonists
(abridged;
full list)
Antagonists
δ-opioid
(DOR)
Agonists
Antagonists
κ-opioid
(KOR)
Agonists
Antagonists
Nociceptin
(NOP)
Agonists
Antagonists
Others
  • Others: Kyotorphin (met-enkephalin releaser/degradation stabilizer)


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