Names | |
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Preferred IUPAC name Fluoro(iodo)methane | |
Other names
Fluoroiodomethane Fluoro-iodo-methane Fluoromethyl iodide | |
Identifiers | |
CAS Number | |
3D model (JSmol) | |
ChemSpider | |
ECHA InfoCard | 100.201.539 |
PubChem CID | |
CompTox Dashboard (EPA) | |
InChI
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SMILES
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Properties | |
Chemical formula | CH2FI |
Molar mass | 159.93 g/mol |
Boiling point | 53.4 °C (128.1 °F; 326.5 K) |
Hazards | |
GHS labelling: | |
Pictograms | |
Signal word | Danger |
Hazard statements | H301, H311, H330 |
Precautionary statements | P260, P264, P270, P271, P280, P284, P301+P310, P302+P352, P304+P340, P310, P312, P320, P321, P322, P330, P361, P363, P403+P233, P405, P501 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa). Y verify (what is ?) Infobox references |
Fluoroiodomethane is the halomethane with the formula FCH2I. Also classified as a fluoroiodocarbon (FIC), it is a colorless liquid. It is a reagent for the introduction of the fluoromethyl (FCH2) group.
Synthesis and uses
It is prepared by fluorination of methylene iodide.
Its isotopomer fluoroiodomethane is used for fluoromethylation of radiopharmaceuticals.
Additional reading
- Zheng L.; Berridge M. S. (January 2000). "Synthesis of [F]fluoromethyl iodide, a synthetic precursor for fluoromethylation of radiopharmaceuticals". Applied Radiation and Isotopes. 52 (1): 55–61(7). doi:10.1016/S0969-8043(99)00061-5. PMID 10670923.
- Chin F. T.; Morse Ch. L.; Shetty H. U.; Pike V. W. (December 2005). "Automated radiosynthesis of [18F]SPA-RQ for imaging human brain NK1 receptors with PET". Journal of Labelled Compounds and Radiopharmaceuticals. 49 (1): 17–31(15). doi:10.1002/jlcr.1016. Retrieved 2007-06-29.
- Tedder, J. M.; Sloan, J. P.; Walton, J. C. (1975). "Free Radical Addition to Olefins, Part XVII. Addition of Fluoroiodomethane to Fluoroethylenes". Journal of the Chemical Society: 1846–1850.
References
- Landelle, Gregory; Paquin, Jean-Francois (2011). "Fluoroiodomethane". Encyclopedia of Reagents for Organic Synthesis. e-EROS Encyclopedia of Reagents for Organic Synthesis. doi:10.1002/047084289X.rn01273. ISBN 978-0471936237.
Halomethanes | |
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Unsubstituted | |
Monosubstituted | |
Disubstituted | |
Trisubstituted | |
Tetrasubstituted | |
* Chiral compound. |
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